Evidence map›Paper›PMID 32584649›Full record

ArticleGut microbes2020

Peptidase PepP is a novel virulence factor of

Markus M Heimesaat, Anna-Maria Schmidt, Soraya Mousavi, Ulrike Escher, Nicole Tegtmeyer, Silja Wessler, Gabriele Gadermaier, Peter Briza, Dirk Hofreuter, Stefan Bereswill and 1 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Therapeutic and protective approaches to combatFrontiers in pharmacology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Treatment with the Probiotic Product AviguardInternational journal of molecular sciences · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Markus M HeimesaatInstitute of Microbiology, Infectious Diseases and Immunology, Gastrointestinal Microbiology Research Group, Charité - University Medicine Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, And Berlin Institute of Health , Berlin, Germany.
Anna-Maria SchmidtInstitute of Microbiology, Infectious Diseases and Immunology, Gastrointestinal Microbiology Research Group, Charité - University Medicine Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, And Berlin Institute of Health , Berlin, Germany.
Soraya MousaviInstitute of Microbiology, Infectious Diseases and Immunology, Gastrointestinal Microbiology Research Group, Charité - University Medicine Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, And Berlin Institute of Health , Berlin, Germany.
Ulrike EscherInstitute of Microbiology, Infectious Diseases and Immunology, Gastrointestinal Microbiology Research Group, Charité - University Medicine Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, And Berlin Institute of Health , Berlin, Germany.
Nicole TegtmeyerDivision of Microbiology, Department of Biology, Friedrich Alexander University Erlangen/Nuremberg , Erlangen, Germany.ORCID 0000-0002-6300-1831
Silja WesslerDepartment of Biosciences, Paris Lodron University of Salzburg , Salzburg, Austria.
Gabriele GadermaierDepartment of Biosciences, Paris Lodron University of Salzburg , Salzburg, Austria.
Peter BrizaDepartment of Biosciences, Paris Lodron University of Salzburg , Salzburg, Austria.
Dirk HofreuterDepartment of Biological Safety, German Federal Institute for Risk Assessment (Bfr) , Berlin, Germany.
Stefan BereswillInstitute of Microbiology, Infectious Diseases and Immunology, Gastrointestinal Microbiology Research Group, Charité - University Medicine Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität Zu Berlin, And Berlin Institute of Health , Berlin, Germany.ORCID 0000-0002-4885-4887
Steffen BackertDivision of Microbiology, Department of Biology, Friedrich Alexander University Erlangen/Nuremberg , Erlangen, Germany.ORCID 0000-0002-8948-8254
Freie Universität Berlin · DEUniversity of Salzburg · ATFriedrich-Alexander-Universität Erlangen-Nürnberg · DEFederal Institute for Risk Assessment · DE

Funding

Austrian Science Fund FWF P 31507
6 · The paper itself

Abstract

Mechanisms of host-pathogen interactions resulting in immunopathological responses upon human

Indexed as

Campylobacter jejuniAnimalsApoptosisCampylobacter InfectionsFemaleFoodborne DiseasesGastrointestinal MicrobiomeGastrointestinal TractInterleukin-10MaleMiceMice, Inbred C57BLMice, KnockoutSerine EndopeptidasesVirulence FactorsIL10 protein, mouseInterleukin-10Serine EndopeptidasesVirulence FactorsCampylobacteriosishost–pathogen interactionM24 peptidase familypepPpro-inflammatory immune responsessecondary abiotic IL-10−/- mouse modelXaa-Pro aminopeptidase

Identifiers

PMID32584649
PMCPMC7524167
OpenAlexW3037674851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.