Evidence map›Paper›PMID 32584606›Full record

ArticleThe British journal of radiology2020

Delayed contrast dynamics as marker of regional impairment in pulmonary fibrosis using 5D MRI - a pilot study.

Maria Ta Buzan, Andreas Wetscherek, Christopher M Rank, Michael Kreuter, Claus Peter Heussel, Marc Kachelrieß, Julien Dinkel

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Maria Ta BuzanDepartment of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany.
Andreas WetscherekMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Christopher M RankMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Michael KreuterTranslational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.
Claus Peter HeusselDepartment of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany.
Marc KachelrießMedical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Julien DinkelDepartment of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany.
Heidelberg University · DEUniversity Hospital Heidelberg · DEInstitute of Cancer Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyse delayed contrast dynamics of fibrotic lesions in interstitial lung disease (ILD) using five dimensional (5D) MRI and to correlate contrast dynamics with disease severity.

methods20 patients (mean age: 71 years; M:F, 13:7), with chronic fibrosing ILD:

resultsIPF lesions showed later peak enhancement compared to non-IPF (severe:

conclusionsContrast agent dynamics are influenced by type and severity of pulmonary fibrosis, which might enable a more thorough characterisation of disease burden. The regional impairment is of particular interest in the context of antifibrotic treatments and was characterised using a non-invasive, non-irradiating, free-breathing method. ADVANCES IN KNOWLEDGE: Delayed contrast enhancement patterns allow the assessment of regional lung impairment which could represent different disease stages or phenotypes in ILD.

Indexed as

AgedConnective Tissue DiseasesContrast MediaFemaleHumansIdiopathic Interstitial PneumoniasIdiopathic Pulmonary FibrosisImage Processing, Computer-AssistedLung Diseases, InterstitialMagnetic Resonance ImagingMaleMiddle AgedMultidetector Computed TomographyOrganometallic CompoundsPilot ProjectsPrincipal Component AnalysisContrast MediagadobutrolOrganometallic Compounds

Identifiers

PMID32584606
PMCPMC7465850
OpenAlexW3037995217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.