Evidence map›Paper›PMID 32584603›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Blood Eosinophil Depletion with Mepolizumab, Benralizumab, and Prednisolone in Eosinophilic Asthma.

Angela M Moran, Sanjay Ramakrishnan, Catherine A Borg, Clare M Connolly, Simon Couillard, Christine M Mwasuku, Ian D Pavord, Timothy S C Hinks, Lauri Lehtimӓki

Open access · hybridAbstract readComparative StudyLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Anti-IL-5 therapies for asthma.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Trial
  3. Trial
  4. Observational
  5. Prioritizing efficacy over convenience.American journal of respiratory and critical care medicine · 2026
    Article
  6. Mechanisms and therapeutic strategies of asthma: from bench to bedside.Signal transduction and targeted therapy · 2026
    Review
  7. Review
  8. Review
  9. Impact of Biologics on Oscillometry Defined Small Airway Dysfunction in Uncontrolled Asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Review
  10. Early and Sustained Asthma Control and Remission in Real-World Patients With Severe Eosinophilic Asthma Treated With Benralizumab: XALOC-2.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Observational
  11. Review
  12. Biological Therapies in Chronic Obstructive Pulmonary Disease: New Directions in Personalised Respiratory Medicine.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Angela M MoranUniversity of Oxford, Oxfordshire, United Kingdom.ORCID 0000-0002-2067-9335
Sanjay RamakrishnanUniversity of Oxford, Oxfordshire, United Kingdom.ORCID 0000-0002-3003-7918
Catherine A BorgUniversity of Oxford, Oxfordshire, United Kingdom.
Clare M ConnollyUniversity of Oxford, Oxfordshire, United Kingdom.
Simon CouillardUniversity of Oxford, Oxfordshire, United Kingdom.ORCID 0000-0002-4057-6886
Christine M MwasukuUniversity of Oxford, Oxfordshire, United Kingdom.
Ian D PavordUniversity of Oxford, Oxfordshire, United Kingdom.
Timothy S C HinksUniversity of Oxford, Oxfordshire, United Kingdom.ORCID 0000-0003-0699-2373
Lauri LehtimӓkiUniversity of Oxford, Oxfordshire, United Kingdom.ORCID 0000-0003-1586-4998
University of Oxford · GBUniversité de Sherbrooke · CA

Funding

Wellcome TrustWellcome Trust 104553/Z/14/ZWellcome Trust 211050/Z/18/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAnti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedAsthmaBlood Chemical AnalysisEosinophilsFemaleGlucocorticoidsHumansMaleMiddle AgedPrednisoloneAnti-Asthmatic AgentsAntibodies, Monoclonal, HumanizedGlucocorticoidsPrednisolone

Identifiers

PMID32584603
PMCPMC7605198
OpenAlexW3037968627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.