ArticleCurrent protocols in neuroscience2020
Chronic Imaging of Mouse Brain: From Optical Systems to Functional Ultrasound.
Article in Current protocols in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Simultaneous Functional Ultrasound, Intrinsic Optical Signal and Widefield Calcium Neuroimaging.bioRxiv : the preprint server for biology · 2026Article
- The protocol for mesoscopic wide-field optical imaging in mice: from zero to hero.Biology methods & protocols · 2026Review
- Brief disruptions in capillary flow result in rapid onset of hypoxia.Neurophotonics · 2025Article
- Optical coherence tomography enables longitudinal evaluation of cell graft-directed remodeling in stroke lesions.Experimental neurology · 2025Article
- The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice.PLoS biology · 2024Article
- Time-Lagged Functional Ultrasound for Multi-Parametric Cerebral Hemodynamic Imaging.IEEE transactions on medical imaging · 2024Article
- High throughput detection of capillary stalling events with Bessel beam two-photon microscopy.Neurophotonics · 2023Article
- Head holder and cranial window design for sequential magnetic resonance imaging and optical imaging in awake mice.Frontiers in neuroscience · 2022Article
- Whole-brain functional ultrasound imaging in awake head-fixed mice.Nature protocols · 2021Article
- Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Utilization of functional ultrasound (fUS) in cerebral vascular imaging is gaining popularity among neuroscientists. In this article, we describe a chronic surgical preparation method that allows longitudinal studies and therefore is applicable to a wide range of studies, especially on aging, stroke, and neurodegenerative diseases. This method can also be used with awake mice; hence, the deleterious effects of anesthesia on neurovascular responses can be avoided. In addition to fUS imaging, this surgical preparation allows researchers to take advantage of common optical imaging methods to acquire complementary datasets to help increase the technical rigor of studies. © 2020 Wiley Periodicals LLC. Basic Protocol 1: Surgical preparation of mouse chronic cranial windows using polymethylpentene Basic Protocol 2: Imaging of mice with chronic cranial windows.
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