Evidence map›Paper›PMID 32584264›Full record

ArticleAging2020

Modulation of attention networks serving reorientation in healthy aging.

Yasra Arif, Rachel K Spooner, Alex I Wiesman, Christine M Embury, Amy L Proskovec, Tony W Wilson

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yasra ArifDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Rachel K SpoonerDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Alex I WiesmanDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Christine M EmburyCenter for Magnetoencephalography, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Amy L ProskovecCenter for Magnetoencephalography, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Tony W WilsonDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE 68198, USA.
University of Nebraska Medical Center · USUniversity of Nebraska at Omaha · US

Funding

Translational Imaging and Behavioral Assessment (TIBA) CoreP20GM130447 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI David E Warren · 2020 to 2026
$20.7M
MULTIMODAL IMAGING OF NEUROHIV DYNAMICS (MIND): AN OMAHA-PITTSBURGH CONSORTIUMR01MH118013 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2022
$4.9M
SIGNATURES OF CANNABIS ABUSE IN NEUROHIV (SCAN): AN INTEGRATED MOLECULAR AND IMAGING APPROACHR01DA047828 · NIDA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BECKER, JAMES T., FOX, HOWARD S · 2018 to 2022
$4.5M
THE PROGRESSIVE ELEVATION OF SPONTANEOUS CORTICAL ACTIVITY IN HAND (PESCAH) PROJECTR01MH116782 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2022
$3.4M
Neurophysiological markers of HAND and the impact of aging: Evidence from MEGR01MH103220 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2014 to 2018
$2.5M
THE IMPACT OF SPONTANEOUS CORTICAL ACTIVITY ON NEURAL OSCILLATIONS AND BEHAVIORAL PERFORMANCE: EVIDENCE FROM HIGH-DEFINITION TDCS AND MEGRF1MH117032 · NIMH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WILSON, TONY W · 2018 to 2018
$2.4M
Neuroimmunology of Disease Training ProgramT32NS105594 · NINDS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI Aditya N Bade, Howard E Gendelman · 2018 to 2026
$1.4M
Oscillatory markers of cognitive deficits in patients with Alzheimer's diseaseF31AG055332 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WIESMAN, ALEX I · 2017 to 2019
$119k
NIA NIH HHS F31 AG055332NIDA NIH HHS R01 DA047828NIGMS NIH HHS P20 GM130447NIMH NIH HHS R01 MH103220NIMH NIH HHS R01 MH116782NIMH NIH HHS R01 MH118013NIMH NIH HHS RF1 MH117032NINDS NIH HHS T32 NS105594
6 · The paper itself

Abstract

Orienting attention to behaviorally relevant stimuli is essential for everyday functioning and mainly involves activity in the dorsal and ventral frontoparietal networks. Many studies have shown declines in the speed and accuracy of attentional reallocation with advancing age, but the underlying neural dynamics remain less understood. We investigated this age-related decline using magnetoencephalography (MEG) and a Posner task in 94 healthy adults (22-72 years old). MEG data were examined in the time-frequency domain, and significant oscillatory responses were imaged using a beamformer. We found that participants responded slower when attention reallocation was needed (i.e., the validity effect) and that this effect was positively correlated with age. We also found age-related validity effects on alpha activity in the left parietal and beta in the left frontal-eye fields from 350-950 ms. Overall, stronger alpha and beta responses were observed in younger participants during attention reallocation trials, but this pattern was reversed in the older participants. Interestingly, this alpha validity effect fully mediated the relationship between age and behavioral performance. In conclusion, older adults were slower in reorienting attention and exhibited age-related alterations in alpha and beta responses within parietal and frontal regions, which may reflect increased task demands depleting their compensatory resources.

Indexed as

AdultAgedAgingAttentionFemaleHealthy AgingHumansMagnetoencephalographyMaleMiddle AgedParietal LobePrefrontal CortexReaction TimeYoung AdultCRUNCHmagnetoencephalographyoscillationsposnervalidity effect

Identifiers

PMID32584264
PMCPMC7377885
OpenAlexW3037740481

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.