ArticlePhysiological research2020
Increasing Veno-Arterial Extracorporeal Membrane Oxygenation Flow Reduces Electrical Impedance of the Lung Regions in Porcine Acute Heart Failure.
Article in Physiological research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- First Real-Time Imaging of Acute Effects of Arteriovenous Fistula on Regional Distribution of Pulmonary Perfusion in a Novel Porcine Model.Physiological research · 2025Article
- Real-time effects of lateral positioning on regional ventilation and perfusion in an experimental model of acute respiratory distress syndrome.Frontiers in physiology · 2023Article
- A large arteriovenous fistula steals a considerable part of systemic blood flow during veno-arterial extracorporeal circulation support in a porcine model.Frontiers in physiology · 2023Article
- Ten years of our translational research in the field of veno-arterial extracorporeal membrane oxygenation.Physiological research · 2022Review
- New Porcine Model of Arteriovenous Fistula Documents Increased Coronary Blood Flow at the Cost of Brain Perfusion.Frontiers in physiology · 2022Article
- Hemodynamic adaptation of heart failure to percutaneous venoarterial extracorporeal circulatory supports.Physiological research · 2020Review
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is a technique used in patients with severe heart failure. The aim of this study was to evaluate its effects on left ventricular afterload and fluid accumulation in lungs with electrical impedance tomography (EIT). In eight swine, incremental increases of extracorporeal blood flow (EBF) were applied before and after the induction of ischemic heart failure. Hemodynamic parameters were continuously recorded and computational analysis of EIT was used to determine lung fluid accumulation. With an increase in EBF from 1 to 4 l/min in acute heart failure the associated increase of arterial pressure (raised by 44%) was accompanied with significant decrease of electrical impedance of lung regions. Increasing EBF in healthy circulation did not cause lung impedance changes. Our findings indicate that in severe heart failure EIT may reflect fluid accumulation in lungs due to increasing EBF.
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