Evidence map›Paper›PMID 32584028›Full record

ArticleBiochemistry2020

Identifying Structural Determinants of Product Specificity in

Sweta Maheshwari, Yu Seon Kim, Srinivas Aripirala, Michael Murphy, L Mario Amzel, Sandra B Gabelli

Open access · greenAbstract read
In one paragraph

Article in Biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sweta MaheshwariDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Yu Seon KimDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Srinivas AripiralaDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Michael MurphyCytiva, Marlborough, Massachusetts 01752, United States.
L Mario AmzelDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Sandra B GabelliDepartment of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.ORCID 0000-0003-1205-5204
Johns Hopkins University · US

Funding

Calmodulin Regulation Na Channels: From Function and Structure to DiseaseR01HL128743 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ALDRICH, RICHARD, AMZEL, L. MARIO · 2016 to 2019
$4.2M
NHLBI NIH HHS R01 HL128743
6 · The paper itself

Abstract

Farnesyl diphosphate synthase (FPPS) is an isoprenoid chain elongation enzyme that catalyzes the sequential condensation of dimethylallyl diphosphate (C

Indexed as

Binding SitesCrystallography, X-RayDiphosphatesDiterpenesGeranyltranstransferaseHemiterpenesHumansLeishmania majorLeishmaniasis, CutaneousModels, MolecularOrganophosphorus CompoundsPolyisoprenyl PhosphatesProtein ConformationSesquiterpenesSubstrate Specificity3,3-dimethylallyl pyrophosphateDiphosphatesDiterpenesfarnesyl pyrophosphategeranyl diphosphateGeranyltranstransferaseHemiterpenesisopentenyl pyrophosphateOrganophosphorus CompoundsPolyisoprenyl PhosphatesSesquiterpenes

Identifiers

PMID32584028
PMCPMC8049779
OpenAlexW3037740701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.