Evidence map›Paper›PMID 32583817›Full record

ArticleChemical communications (Cambridge, England)2020

Disassembly of polymeric nanoparticles with enzyme-triggered polymer unzipping: polyelectrolyte complexes vs. amphiphilic nanoassemblies.

Vikash Kumar, Oyuntuya Munkhbat, Hatice Secinti, S Thayumanavan

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Self-Immolative Polyion Complexes.Macromolecular rapid communications · 2025
    Article
  2. Article
  3. Article
  4. Multichannel dual protein sensing using amphiphilic supramolecular assemblies.Chemical communications (Cambridge, England) · 2021
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vikash KumarDepartment of Chemistry, University of Massachusetts, Amherst, MA-01003, USA. thai@umass.edu.
Oyuntuya MunkhbatDepartment of Chemistry, University of Massachusetts, Amherst, MA-01003, USA. thai@umass.edu.
Hatice SecintiDepartment of Chemistry, University of Massachusetts, Amherst, MA-01003, USA. thai@umass.edu.ORCID http://orcid.org/0000-0002-6665-3448
S ThayumanavanDepartment of Chemistry, University of Massachusetts, Amherst, MA-01003, USA. thai@umass.edu and Centre for Bioactive Delivery, Institute for Applied Life Science, University of Massachusetts, Amherst, MA-01003, USA and Molecular and Cellular Biology Program, University of Massachusetts, Amherst, MA-01003, USA.ORCID http://orcid.org/0000-0002-6475-6726

Funding

Protein-Induced Self-Assembly and Disassembly of Nanostructures Based on OligoR35GM136395 · NIGMS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI Sankaran Thayumanavan · 2020 to 2026
$3.5M
NIGMS NIH HHS R35 GM136395
6 · The paper itself

Abstract

Alkaline phosphatase (ALP) responsive polymers, which can unzip from head to tail are reported. Hydrophilic and hydrophobic modification of the polymer was carried out for the formation of a polyelectrolyte complex and an amphiphilic nanoassembly, respectively, which offered distinct enzyme-triggered disassembly kinetics.

Indexed as

Alkaline PhosphataseHydrophobic and Hydrophilic InteractionsKineticsNanoparticlesPolyelectrolytesPolymersAlkaline PhosphatasePolyelectrolytesPolymers

Identifiers

PMID32583817
PMCPMC7390689

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.