SynthesisIndian pediatrics2020
Clinical Features and Outcome of SARS-CoV-2 Infection in Children: A Systematic Review and Meta-analysis.
Synthesis in Indian pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Evidence linking COVID-19 and the health/well-being of children and adolescents: an umbrella review.BMC medicine · 2024Pooled it
- Clinical Features and Outcome of SARS-CoV-2 Infection in Neonates: A Systematic Review.Journal of tropical pediatrics · 2021Pooled it
- COVID-19 under 19: A meta-analysis.Pediatric pulmonology · 2021Pooled it
- Clinical presentations and outcomes of children with cancer and COVID-19: A systematic review.Pediatric blood & cancer · 2021Pooled it
- Article
- Clinical Outcomes of Pediatric Cancer Patients with COVID-19: A Cross-Sectional Study.International journal of hematology-oncology and stem cell research · 2024Article
- Factors Associated with Adverse Outcomes among SARS-CoV-2 Positive Children in a Tertiary Government COVID-19 Referral Hospital in the Philippines.Acta medica Philippina · 2024Article
- Pediatric COVID-TB: A Clinical Perspective Based on the Analysis of Three Cases.Children (Basel, Switzerland) · 2023Article
- Mortality patterns among COVID-19 patients in two Saudi hospitals: Demographics, etiology, and treatment.Influenza and other respiratory viruses · 2023Article
- Abdominal Manifestations of Multisystem Inflammatory Syndrome in Children: A Single-Center Experience.Indian pediatrics · 2022Review
- Manifestations of COVID-19 infection in children with malignancy: A single-center experience in Jordan.World journal of virology · 2022Article
- Clinicolaboratory Profile, Treatment, Intensive Care Needs, and Outcome of Pediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2: A Systematic Review and Meta-analysis.Journal of pediatric intensive care · 2022Review
- Predictors of mortality in children admitted with SARS-CoV-2 infection to a tertiary care hospital in North India.Journal of paediatrics and child health · 2022Article
- COVID-19 in children: clinical and epidemiological spectrum in the community.European journal of pediatrics · 2022Observational
- Vaccination With Routine Childhood Vaccines and Severity of COVID-19 Among Children in Delhi.Indian pediatrics · 2022Article
- Hematological changes associated with COVID-19 infection.Journal of clinical laboratory analysis · 2022Review
- Clinical and Laboratory Features of PCR-Confirmed and Clinically Suspected COVID-19 Pediatric Patients: A Single Hospital-Based Experience During the First COVID-19 Wave in the United Arab Emirates.Frontiers in pediatrics · 2022Article
- Clinical characteristics & outcome of SARS-CoV-2 infected neonates presenting to paediatric emergency.The Indian journal of medical research · 2022Article
- Development of an Enzyme-Linked Immunosorbent Assay (ELISA) for Accurate and Prompt Coronavirus Disease 2019 (COVID-19) Diagnosis Using the Rational Selection of Serological Biomarkers.Diagnostics (Basel, Switzerland) · 2021Article
- COVID-19 in Children: What We Know and What We Don't Know?Indian journal of pediatrics · 2021Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveKnowledge about COVID-19 in children is limited due to the paucity of reported data. The pediatric age group comprises only less than 5% of total COVID-19 worldwide, therefore, large studies in this population are unlikely in the immediate future. Hence, we planned to synthesize the current data that will help in a better understanding of COVID-19 in children. EVIDENCE ACQUISITION: Four different electronic databases (MEDLINE, EMBASE, Web of Science, and CENTRAL) were searched for articles related to COVID-19 in the pediatric population. We included studies reporting disease characteristics and outcomes of COVID-19 in patients aged less than 19 years. We performed a random-effect meta-analysis to provide pooled estimates of various disease characteristics.
results27 studies (4857 patients) fulfilling the eligibility criteria were included in this systematic review, from a total of 883 records. About half of the patients had each of fever and cough, 11% (6-17%) had fast breathing, and 6-13% had gastrointestinal manifestations. Most of the patients had mild to moderate disease, and only 4% had a severe or critical illness. Leukopenia was the commonest reported laboratory abnormality.
conclusionsEven among the symptomatic COVID-19 cases, severe manifestations are seen in very few children. Though fever and respiratory symptoms are most common, many children also have gastrointestinal manifestations.
Indexed as
Identifiers
32583808PMC7498550What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.