Evidence map›Paper›PMID 32583744›Full record

ArticleMolecular biology of the cell2020

Hydrogen peroxide induces Arl1 degradation and impairs Golgi-mediated trafficking.

Stephen C Ireland, Haoran Huang, Jianchao Zhang, Jie Li, Yanzhuang Wang

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Golgi defect as a major contributor to lysosomal dysfunction.Frontiers in cell and developmental biology · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Common Markers and Small Molecule Inhibitors in Golgi Studies.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  11. Common Assays in Mammalian Golgi Studies.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Adaptation of the Golgi Apparatus in Cancer Cell Invasion and Metastasis.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Stephen C IrelandDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085.
Haoran HuangDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085.
Jianchao ZhangDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085.
Jie LiDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085.
Yanzhuang WangDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-1085.
University of Michigan–Ann Arbor · US

Funding

Supplement: GOLGI BIOGENESIS AND FUNCTIONR35GM130331 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, YANZHUANG · 2019 to 2023
$2.7M
Supplement: GOLGI BIOGENESIS AND FUNCTIONR01GM112786 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, YANZHUANG · 2015 to 2019
$1.3M
Golgi-mediated Glycosylation Defects in Alzheimer’s DiseaseR56AG062225 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, YANZHUANG · 2018 to 2018
$527k
NIA NIH HHS R56 AG062225NIGMS NIH HHS R01 GM112786NIGMS NIH HHS R35 GM130331
6 · The paper itself

Abstract

Reactive oxygen species (ROS)-induced oxidative stress has been associated with diseases such as amyotrophic lateral sclerosis, stroke, and cancer. While the effect of ROS on mitochondria and endoplasmic reticulum (ER) has been well documented, its consequence on the Golgi apparatus is less well understood. In this study, we characterized the Golgi structure and function in HeLa cells after exposure to hydrogen peroxide (H

Indexed as

ADP-Ribosylation FactorsAutoantigensBiological TransportGolgi ApparatusGolgi Matrix ProteinsHeLa CellsHumansHydrogen PeroxideIntracellular MembranesMembrane ProteinsMitochondriaOxidative StressProtein TransportReactive Oxygen Speciestrans-Golgi NetworkADP-ribosylation factor related proteinsADP-Ribosylation FactorsAutoantigensGolgi complex autoantigen, 97-kDaGolgi Matrix ProteinsHydrogen PeroxideMembrane ProteinsReactive Oxygen Species

Identifiers

PMID32583744
PMCPMC7525819
OpenAlexW3036028289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.