ArticleTransplant infectious disease : an official journal of the Transplantation Society2020
COVID-19 in recent heart transplant recipients: Clinicopathologic features and early outcomes.
Article in Transplant infectious disease : an official journal of the Transplantation Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 8 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- COVID-19 Convalescent Plasma for the Treatment of Immunocompromised Patients: A Systematic Review and Meta-analysis.JAMA network open · 2023Pooled it
- SARS-CoV-2 infection in heart transplant recipients: a systematic literature review of clinical outcomes and immunosuppression strategies.Heart failure reviews · 2022Pooled it
- COVID-19 in heart transplant recipients during February-August 2020: A systematic review.Clinical transplantation · 2021Pooled it
- Effect of immunosuppression maintenance in solid organ transplant recipients with COVID-19: Systematic review and meta-analysis.Transplant infectious disease : an official journal of the Transplantation Society · 2021Pooled it
- The Effect of Convalescent Plasma Therapy on Mortality Among Patients With COVID-19: Systematic Review and Meta-analysis.Mayo Clinic proceedings · 2021Pooled it
- Clinical manifestations and outcomes of coronavirus disease-19 in heart transplant recipients: a multicentre case series with a systematic review and meta-analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2021Pooled it
- COVID-19 in immunocompromised patients: A systematic review of cancer, hematopoietic cell and solid organ transplant patients.The Journal of infection · 2021Pooled it
- COVID-19 in solid organ transplant recipients: A systematic review and meta-analysis of current literature.Transplantation reviews (Orlando, Fla.) · 2021Pooled it
- Racial Disparities in Coronavirus Disease 2019 Mortality Are Present in Heart Transplant Recipients.The Annals of thoracic surgery · 2023Article
- Orthotopic Heart Transplantation in a Covid-19 Recipient.Arquivos brasileiros de cardiologia · 2023Article
- Measuring the effect of the COVID-19 pandemic on solid organ transplantation.American journal of surgery · 2022Article
- Potential use of convalescent plasma for SARS-CoV-2 prophylaxis and treatment in immunocompromised and vulnerable populations.Expert review of vaccines · 2022Article
- COVID-19 in heart transplant recipients: Outcomes according to vaccination status.Transplant infectious disease : an official journal of the Transplantation Society · 2022Article
- Early report from the Pediatric Heart Transplant Society on COVID-19 infections in pediatric heart transplant candidates and recipients.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022Article
- Heart failure in COVID-19 patients: Critical care experience.World journal of virology · 2022Review
- Evolution of Clinical Care in COVID-Infected Solid Organ Transplant Recipients.Current transplantation reports · 2022Review
- Impact of COVID-19 Infection Among Heart Transplant Recipients: A Southern Brazilian Experience.Frontiers in medicine · 2022Article
- Impact of COVID-19 infection on the cardiovascular system: An evidence-based analysis of risk factors and outcomes.Best practice & research. Clinical anaesthesiology · 2021Review
- SARS-CoV-2 in Solid Organ Transplant Recipients: A Structured Review of 2020.Transplantation proceedings · 2021Review
- Is Early COVID-19 in Kidney Transplant Recipients Concerning Enough to Halt Transplantation? A Multicenter Comparative Analysis from India.Transplantation proceedings · 2021Article
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of COVID-19 on heart transplant (HTx) recipients remains unclear, particularly in the early post-transplant period.
methodsWe share novel insights from our experience in five HTx patients with COVID-19 (three within 2 months post-transplant) from our institution at the epicenter of the pandemic.
resultsAll five exhibited moderate (requiring hospitalization, n = 3) or severe (requiring ICU and/or mechanical ventilation, n = 2) illness. Both cases with severe illness were transplanted approximately 6 weeks before presentation and acquired COVID-19 through community spread. All five patients were on immunosuppressive therapy with mycophenolate mofetil (MMF) and tacrolimus, and three that were transplanted within the prior 2 months were additionally on prednisone. The two cases with severe illness had profound lymphopenia with markedly elevated C-reactive protein, procalcitonin, and ferritin. All had bilateral ground-glass opacities on chest imaging. MMF was discontinued in all five, and both severe cases received convalescent plasma. All three recent transplants underwent routine endomyocardial biopsies, revealing mild (n = 1) or no acute cellular rejection (n = 2), and no visible viral particles on electron microscopy. Within 30 days of admission, the two cases with severe illness remain hospitalized but have clinically improved, while the other three have been discharged.
conclusionsCOVID-19 appears to negatively impact outcomes early after heart transplantation.
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