Evidence map›Paper›PMID 32583484›Full record

ArticleMedical physics2020

Scintillation imaging as a high-resolution, remote, versatile 2D detection system for MR-linac quality assurance.

Daniel A Alexander, Rongxiao Zhang, Petr Brůža, Brian W Pogue, David J Gladstone

Abstract read
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniel A AlexanderThayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA.ORCID https://orcid.org/0000-0003-3831-7479
Rongxiao ZhangThayer School of Engineering and Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.ORCID https://orcid.org/0000-0002-0423-7828
Petr BrůžaThayer School of Engineering, Dartmouth College, Hanover, NH, 03755, USA.ORCID https://orcid.org/0000-0002-6196-5872
Brian W PogueThayer School of Engineering and Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.ORCID https://orcid.org/0000-0002-9887-670X
David J GladstoneThayer School of Engineering and Geisel School of Medicine, Dartmouth College, Hanover, NH, 03755, USA.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
OPTICAL CHERENKOV IMAGING DOSIMETRY IN HUMAN RADIOTHERAPYR01EB023909 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI GLADSTONE, DAVID J., JARVIS, LESLEY A · 2017 to 2024
$4.4M
Video Rate optical verification tool for radiotherapy treatment plansR44CA199681 · NCI · DOSEOPTICS, LLC · PI WARE, WILLIAM · 2016 to 2017
$2.0M
NCI NIH HHS P30 CA023108NCI NIH HHS R44 CA199681NIBIB NIH HHS R01 EB023909
6 · The paper itself

Abstract

purposeTo demonstrate the potential benefits of remote camera-based scintillation imaging for routine quality assurance (QA) measurements for magnetic resonance guided radiotherapy (MRgRT) linear accelerators.

methodsA wall-mounted CMOS camera with a time-synchronized intensifier was used to image photons produced from a scintillation screen in response to dose deposition from a 6 MV FFF x-ray beam produced by a 0.35 T MR-linac. The oblique angle of the field of view was corrected using a projective transform from a checkerboard calibration target. Output sensitivity and constancy was measured using the scintillator and benchmarked against an A28 ion chamber. Field cross-plane and in-plane profiles were measured for field sizes ranging from 1.68 × 1.66 cm

resultsThe scintillation imaging system showed comparable sensitivity and linearity to the ion chamber in response to changes in machine output down to 0.5 MU (R

conclusionsRemote scintillation imaging of a two-dimensional screen provided a rapid, versatile, MR-compatible solution to many routine quality assurance procedures including output constancy, profile flatness and symmetry constancy, MLC position verification and isocenter size. This method is high-resolution, does not require post-irradiation readout, and provides simple, instantaneous data acquisition. Full automation of the readout and processing could make this a very simple but effective QA tool, and is adaptable to all medical accelerators.

Indexed as

Particle AcceleratorsRadiotherapy, Image-GuidedCalibrationPhotonsMR-linacoptical imagingQAscintillation

Identifiers

PMID32583484
PMCPMC10363284

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.