Evidence map›Paper›PMID 32583364›Full record

ReviewMolecular biotechnology2020

Application of Various Delivery Methods for CRISPR/dCas9.

Zhixi Liu, Zhi Liao, Yan Chen, Lizhu Han, Qinan Yin, Hongtao Xiao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. CRISPR/Cas9 systems: Delivery technologies and biomedical applications.Asian journal of pharmaceutical sciences · 2023
    Review
  7. CRISPR-based mFrontiers in cell and developmental biology · 2023
    Review
  8. Review
  9. Review
  10. Single-Step Genome Editing of Small Ruminant Embryos by Electroporation.International journal of molecular sciences · 2022
    Article
  11. Article
  12. Review
  13. Overexpression ofBiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhixi LiuDepartment of Clinical Pharmacy, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu, 610041, Sichuan, China.
Zhi LiaoDepartment of Gynecology and Obstetrics, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China.
Yan ChenDepartment of Clinical Pharmacy, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu, 610041, Sichuan, China.
Lizhu HanPersonalized Drug Therapy Key Laboratory of Sichuan Province, Chengdu, China.
Qinan YinPersonalized Drug Therapy Key Laboratory of Sichuan Province, Chengdu, China.
Hongtao XiaoDepartment of Clinical Pharmacy, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, No. 55, Section 4, South Renmin Road, Chengdu, 610041, Sichuan, China. xht927@163.com.ORCID http://orcid.org/0000-0003-1725-7550

Funding

Chengdu City Science and Technology Project Grant no.11PPYB010SF-289Sichuan Cancer Hospital Grant no. YB2019001the Cadre Health Care Research Project of Sichuan Province Grant No. 2019-801the Health Department of Sichuan Province Grant nos. 100491, 120111, and 17ZD038the National Key Specialty Construction Project of Clinical Pharmacy Grant no.30305030698the Science & Technology Program of Sichuan Province Grant nos. 2009SZ0226, 2014FZ0103, 2015JQO027, and 2015ZR0160the Young Scholars Foundation of Sichuan Provincial People's Hospital Grant nos. 30305030606 and 30305030859ZambonPharmaceutical Scientific Research Foundation of the Chengdu Pharmaceutical Association Grant No. 201905
6 · The paper itself

Abstract

As gene-editing technology has become more and more popular in the life sciences, CRISPR has brought good news to scientific researchers because of its efficiency, convenience, and wide application. Its wide application has also promoted the development of basic scientific research, agriculture, basic medicine, and clinical treatment. However, how the CRISPR/dCas9 system is effectively delivered to the target organs or cells is still unknown. This paper briefly introduces the CRISPR/dCas9 system and then lists some common delivery methods and their characteristics.

Indexed as

CRISPR-Cas SystemsDrug Delivery SystemsGene EditingAnimalsDrug CarriersElectroporationGenetic VectorsHumansMiceDrug CarriersCRISPRdCas9Delivery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.