ArticleInternational journal of clinical oncology2020
Evaluation of the concordance in HPV type between self- and physician-collected samples using a brush-based device and a PCR-based HPV DNA test in Japanese referred patients with abnormal cytology or HPV infection.
Article in International journal of clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Self-Collected Vaginal Specimens for HPV Testing: Recommendations From the Enduring Consensus Cervical Cancer Screening and Management Guidelines Committee.Journal of lower genital tract disease · 2025Guideline
- Human papillomavirus self-sampling in Asia: a systematic review.Frontiers in microbiology · 2025Pooled it
- Assessment of HPV screening modalities within primary care: a systematic review.Frontiers in medicine · 2025Pooled it
- Trial
- Implementation of a self-sampling HPV test for non-responders to cervical cancer screening in Japan: secondary analysis of the ACCESS trial.Scientific reports · 2022Trial
- Standardizing vaginal microbial profiling: evaluating swab materials, storage conditions, and host DNA depletion strategies.BMC microbiology · 2026Article
- HPV self-sampling and physician-collected sampling for detection of precancerous lesions of the cervix.Bioinformation · 2026Article
- Experiences of Self-Collected Human Papilloma Virus (HPV) Testing Among Women Aged 20 to 65 Years in Ho Chi Minh City, Vietnam.Diagnostics (Basel, Switzerland) · 2025Article
- Acceptability and validity of HPV self-sampling for cervical cancer screening among women living in different ecological settings in India.International journal of cancer · 2025Article
- Prevalence of High-Risk HPV Infection in Community Women at Ho Chi Minh City in 2024: A Cross-Sectional Study with Self-Collect Sampling.International journal of women's health · 2025Article
- Human Papillomavirus Self-Sampling for Unscreened Women Aged 24 Years During the COVID-19 Pandemic.Healthcare (Basel, Switzerland) · 2024Article
- Variables that impact HPV test accuracy during vaginal self collection workflow for cervical cancer screening.Gynecologic oncology reports · 2024Review
- Human Papillomavirus Genotype Detection and Cytology Using a New Self-Sampling Method.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Evaluating Opt-In Vaginal Human Papillomavirus Self-Sampling: Participation Rates and Detection of High-Grade Lesions (CIN2+) among Unscreened Japanese Women Aged 30-39.Healthcare (Basel, Switzerland) · 2024Article
- The impact of alternate HPV vaccination and cervical screening strategies in Japan: a cost-effectiveness analysis.The Lancet regional health. Western Pacific · 2024Article
- Absorbable cyst brushes.Biomedical microdevices · 2023Article
- Mailing human papillomavirus self-sampling kits to women under-screened for cervical cancer improved detection in cervical cancer screening in a general population study in Japan.BMC public health · 2023Article
- Validity and acceptance of self vs conventional sampling for the analysis of human papillomavirus and Pap smear.Scientific reports · 2023Article
- Acceptability and Preference for Human Papilloma Virus Self-Sampling among Thai Women Attending National Cancer Institute.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Evaluation of the feasibility of human papillomavirus sponge-type self-sampling device at Japanese colposcopy clinics.The journal of obstetrics and gynaecology research · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo adopt HPV self-sampling in Japan, we assessed the concordance between self- and physician-collected human papillomavirus (HPV) samples from Japanese patients and examined the performance of HPV self-sampling for cervical intraepithelial neoplasia grade 2 or worse (CIN2+).
methodsPatients who had previously tested negative for intraepithelial lesions or malignancy/HPV-positive, and patients with atypical squamous cells of undetermined significance or worse (ASCUS+) cytology were eligible for this cross-sectional study. Participants performed HPV self-sampling using an Evalyn brush, which was submitted at the Fukui Prefectural Health Care Association. The Evalyn brush heads were stored in ThinPrep vials. The physician, however, performed HPV and cell sampling using an endocervical brush and immediately stored the brush heads in ThinPrep vials. All participants underwent colposcopy and biopsy. Histopathological diagnoses were made by pathologists at Fukui University Hospital. HPV infection was confirmed using a PCR-based Cobas 4800 HPV DNA test. Cytological analysis was performed at Fukui Prefectural Health Care Association.
resultsHPV-positive rates for physician-collected samples and self-collected samples were 51 and 50%, respectively. The perfect match rate of HPV type between the groups was 88% (κ = 0.76). HPV16/18 showed higher agreement rates than other HPVs (99%, kappa 0.96 and 89% kappa 0.77, respectively). Both groups showed 100% sensitivity to CIN2+, but specificity was 57.0 and 58.1%, respectively.
conclusionFor HPV typing, a good concordance rate was seen between self- and physician-collected samples. Self-sampling showed high sensitivity for CIN2+. Self-sampling using the Evalyn brush and Cobas 4800 may be feasible for screening Japanese individuals.
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