Evidence map›Paper›PMID 32583032›Full record

SynthesisWorld journal of microbiology & biotechnology2020

Spent brewer's yeast as a source of high added value molecules: a systematic review on its characteristics, processing and potential applications.

Gabriela Vollet Marson, Ruann Janser Soares de Castro, Marie-Pierre Belleville, Miriam Dupas Hubinger

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of microbiology & biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Frontiers in nutrition · 2026
    Pooled it
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  5. Review
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  11. Review
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  13. Review
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  15. Review
  16. Article
  17. Spent Brewer's Yeast Lysis Enables aInternational journal of molecular sciences · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gabriela Vollet MarsonInstitut Européen des Membranes, Université de Montpellier, CNRS, ENSCM, UM, CC 047, 2 Place Eugène Bataillon, 34095, Montpellier, France. gabrielavollet@gmail.com.ORCID http://orcid.org/0000-0001-7733-1666
Ruann Janser Soares de CastroDepartment of Food Science, School of Food Engineering, UNICAMP, Rua Monteiro Lobato, 80, Campinas, SP, 13083-862, Brazil.ORCID http://orcid.org/0000-0003-2649-8567
Marie-Pierre BellevilleInstitut Européen des Membranes, Université de Montpellier, CNRS, ENSCM, UM, CC 047, 2 Place Eugène Bataillon, 34095, Montpellier, France.ORCID http://orcid.org/0000-0001-9157-9713
Miriam Dupas HubingerLaboratory of Process Engineering, Department of Food Engineering, School of Food Engineering, UNICAMP, Rua Monteiro Lobato, 80, Campinas, SP, 13083-862, Brazil.ORCID http://orcid.org/0000-0002-9933-3969
École Nationale Supérieure de Chimie de Montpellier · FRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 306461-2017-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/18465-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/04067-6
6 · The paper itself

Abstract

Development of new strategies to add-value to agro-industrial by-products are of environmental and economical importance. Innovative and low-cost sources of protein and bioactive peptides have been explored worldwide. Spent brewer's yeast (SBY) is the second most relevant by-product from the brewing industry, and despite its nutritional (about 50% protein, dry weight) and technological potential, it is still underused or needs to be disposed of. SBY cells need to be disrupted to release intracellular and cell wall proteins. This procedure has been performed using autolysis, glass bead milling, enzymatic hydrolysis and ultrasound processing. Enzymatic treatment is usually performed without prior purification and is a challenging process, which involves multiple factors, but has been successfully used as a strategy to add value to agro-industrial by-products. Scope and approach: in this review, we particularly focused on enzymatic hydrolysis as a strategy to promote SBY valorisation, illustrating the state-of-the-art processes used to produce protein extracts from this material as well as exploring fundamental concepts related to the particularities of yeast cell disruption and protein hydrolysis. Furthermore, innovative applications of value-added yeast by-products in food, biotechnological and pharmaceutical industries are presented and discussed. Key findings and conclusions: the discovery of valuable compounds found in spent yeasts as well as the development of new processing methodologies have been widening the possibilities of reuse and transformation of SBY as an ingredient and innovative matrix. Once released, yeast proteins and peptides may be applied as an innovative non-animal protein source or a functional and bioactive ingredient.

Indexed as

Food HandlingNutritive ValueAnimal FeedBeerBiomassCell WallDatabases, FactualFermentationFungal Proteinsgamma-Aminobutyric AcidHydrolysisKynurenic AcidPolyphenolsSaccharomyces cerevisiaeFungal Proteinsgamma-Aminobutyric AcidKynurenic AcidPolyphenolsAlternative sources of proteinAutolysisBeer by-productsEnzymatic hydrolysisSaccharomyces sp.Yeast peptides

Identifiers

PMID32583032
OpenAlexW3037966704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.