Evidence map›Paper›PMID 32582732›Full record

ArticleFrontiers in medicine2020

An Overground Robotic Gait Training Program for People With Multiple Sclerosis: A Protocol for a Randomized Clinical Trial.

Rakel Berriozabalgoitia, Begoña Sanz, Ana Belén Fraile-Bermúdez, Erika Otxoa, Izaskun Yeregui, Iraia Bidaurrazaga-Letona, Iratxe Duñabeitia, Alfredo Antigüedad, Maria Domercq, Jon Irazusta and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Rakel BerriozabalgoitiaADEMBI, Multiple Sclerosis Association of Bizkaia, Bilbao, Spain.
Begoña SanzDepartment of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.
Ana Belén Fraile-BermúdezDepartment of Nursing I, Faculty of Medicine and Nursery, University of the Basque Country (UPV/EHU), Leioa, Spain.
Erika OtxoaADEMBI, Multiple Sclerosis Association of Bizkaia, Bilbao, Spain.
Izaskun YereguiADEMBI, Multiple Sclerosis Association of Bizkaia, Bilbao, Spain.
Iraia Bidaurrazaga-LetonaDepartment of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.
Iratxe DuñabeitiaDepartment of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.
Alfredo AntigüedadBiocruces-Bizkaia Research Institute, Department of Neurology, Cruces University Hospital, Osakidetza Basque Health Service, Barakaldo, Spain.
Maria DomercqDepartment of Neurosciences, University of the Basque Country, Achucarro Basque Center for Neuroscience-UPV/EHU, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Leioa, Spain.
Jon IrazustaDepartment of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.
Ana Rodriguez-LarradDepartment of Physiology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain.
University of the Basque Country · ESAchucarro Basque Center for Neuroscience · ESBioCruces Health research Institute · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintaining the ability to walk is one of the significant challenges in people with multiple sclerosis (MS) for keeping a good quality of life as the disease and the aging process progresses. Overground robotic (OR) wearable exoskeletons are promising tools for gait rehabilitation, but currently there is no evidence of their clinical effects on patients with MS. The present study aims to determine the effects of an OR intervention in people with MS and moderate to severe walking disabilities and ascertain if benefits are maintained over a follow-up period of 3 months. This randomized controlled trial will include 36 participants with MS. Inclusion criteria are: older than 18 years, definitive diagnosis of MS, 4.5-7 points on the EDSS (Expanded Disability Status Scale), and needing one or two canes or crutches for walking outdoors. Subjects in the control group will receive conventional physiotherapy sessions at ADEMBI (Asociación de Esclerosis Múltiple de Bizkaia) provided to control spasticity, maintain articular range and exercise balance. Subjects in the intervention group will receive the same physiotherapy but also participate in a progressive OR gait training program assisted by the Ekso

Indexed as

exoskeletongait speedinflammation biomarkersmultiple sclerosisquality of liferehabilitation

Identifiers

PMID32582732
PMCPMC7295911
OpenAlexW3034726216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.