ReviewFrontiers in bioengineering and biotechnology2020
Functional Biomaterials for Treatment of Chronic Wound.
Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed.
- Clinical application of traditional Chinese medicine powder in the treatment of acute and chronic wounds.International wound journal · 2023Trial
- Review
- Evaluating 3D-Patch Efficacy in Wound Healing Using the Medicinal LeechNanomaterials (Basel, Switzerland) · 2026Article
- The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026Review
- Rethinking Chronic Wound Treatment: Unlocking the Potential of Combination Products for an Unmet Multifactorial Need: A Review Study.Health science reports · 2026Article
- Bio-enhanced silk fibroin-based scaffolds for chronic diabetic foot ulcers.Burns & trauma · 2026Review
- A Glucose-Responsive Hydrogel with Multifunctional Properties for Accelerated Diabetic Wound Healing.Biomaterials research · 2026Article
- Investigation of multifaceted wound healing effect of exopolysaccharide (EPS) produced from probiotic strain Lactiplantibacillus plantarum GD2 as in vitro and in ovo.Scientific reports · 2025Article
- Advances in Designer Materials for Chronic Wound Healing.Advances in wound care · 2025Review
- Phytotherapeutic evaluation of rosehip seed and olive oils on wound healing: evidence from L929 cell culture and in vivo VEGF/TGF-β analysis.3 Biotech · 2025Article
- The Potential of Functional Hydrogels in Burns Treatment.Gels (Basel, Switzerland) · 2025Review
- From Wound Dressing to Tissue Regeneration: Bilayer Medicated Patches for Personalized Treatments of Chronic Wounds.ACS applied materials & interfaces · 2025Article
- Marine Jellyfish Collagen and Other Bioactive Natural Compounds from the Sea, with Significant Potential for Wound Healing and Repair Materials.Marine drugs · 2025Article
- Revealing the promising era of silk-based nanotherapeutics: a ray of hope for chronic wound healing treatment.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Poly(vinyl alcohol)/Gentamicin and Poly(vinyl alcohol)/Chitosan/Gentamicin: Promising Materials for Rapid Burn Wound Healing.Gels (Basel, Switzerland) · 2025Article
- Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings.Gels (Basel, Switzerland) · 2025Review
- Multifunctional poloxamer-based thermo-responsive hydrogel loaded with human lactoferricin niosomes:International journal of pharmaceutics: X · 2024Article
- Granular Porous Nanofibrous Microspheres Enhance Cellular Infiltration for Diabetic Wound Healing.ACS nano · 2024Article
- The role of adipose tissue-derived stromal cells, macrophages and bioscaffolds in cutaneous wound repair.Biology direct · 2024Review
- Bacteria-Derived Cellulose Membranes Modified with Graphene Oxide-Silver Nanoparticles for Accelerating Wound Healing.ACS applied bio materials · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing number of patients with chronic wounds caused by diseases, such as diabetes, malignant tumors, infections, and vasculopathy, has caused severe economic and social burdens. The main clinical treatments for chronic wounds include the systemic use of antibiotics, changing dressings frequently, operative debridement, and flap repair. These routine therapeutic strategies are characterized by a long course of treatment, substantial trauma, and high costs, and fail to produce satisfactory results. Biomaterial dressings targeting the different stages of the pathophysiology of chronic wounds have become an active research topic in recent years. In this review, after providing an overview of the epidemiology of chronic wounds, and the pathophysiological characteristics of chronic wounds, we highlight the functional biomaterials that can enhance chronic wound healing through debridement, anti-infection and antioxidant effects, immunoregulation, angiogenesis, and extracellular matrix remodeling. It is hoped that functional biomaterials will resolve the treatment dilemma for chronic wounds and improve patient quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.