Evidence map›Paper›PMID 32582518›Full record

ArticleInternational cancer conference journal2020

NK-92 cellular therapy for pediatric relapsed/refractory Ewing sarcoma.

Koray Yalcin, Ercument Ovali, Umut Ozdamarlar, Suna Celen, Gulsun Karasu, Akif Yesilipek, Volkan Hazar

Open access · greenAbstract readCase Reports
In one paragraph

Article in International cancer conference journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Koray YalcinPediatric Hematology/Oncology and Stem Cell Transplantation Department, Medical Park Goztepe Hospital, Istanbul, Turkey.
Ercument OvaliAcibadem Labcell Cellular Therapy Center, Istanbul, Turkey.
Umut OzdamarlarBahcesehir University, Faculty of Medicine, Radiology, Istanbul, Turkey.
Suna CelenPediatric Hematology/Oncology and Stem Cell Transplantation Department, Medical Park Goztepe Hospital, Istanbul, Turkey.
Gulsun KarasuPediatric Hematology/Oncology and Stem Cell Transplantation Department, Medical Park Goztepe Hospital, Istanbul, Turkey.
Akif YesilipekPediatric Hematology/Oncology and Stem Cell Transplantation Department, Medical Park Goztepe Hospital, Istanbul, Turkey.
Volkan HazarPediatric Hematology/Oncology and Stem Cell Transplantation Department, Medical Park Goztepe Hospital, Istanbul, Turkey.
Istanbul Eye Hospital · TRAcıbadem University · TRBahçeşehir University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relapsed/refractory Ewing sarcoma prognosis is dreadful, especially for recurrences within the first 2 years after initial diagnosis. It is obvious that there is an urgent need for novel treatment strategies for this dismal situation. NK-92 is an activated NK cell line with high cytotoxicity against malignant cells. Here, we present a relapsed/refractory Ewing sarcoma case who had no response to conventional strategies and recieved intratumoral NK-92 cell injections. We observe that intratumoral injection of NK-92 is safe, has no toxicity and shows preliminary evidence of tumor response in relapsed/refractory Ewing Sarcoma.

Indexed as

Ewing’s sarcomaImmunotherapyNK-92

Identifiers

PMID32582518
PMCPMC7297928
OpenAlexW3013031731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.