Evidence map›Paper›PMID 32582299›Full record

ArticleFrontiers in genetics2020

Genome Data Uncover Conservation Status, Historical Relatedness and Candidate Genes Under Selection in Chinese Indigenous Pigs in the Taihu Lake Region.

Chenxi Liu, Pinghua Li, Wuduo Zhou, Xiang Ma, Xiaopeng Wang, Yan Xu, Nengjing Jiang, Moran Zhao, Tianwei Zhou, Yanzhen Yin and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Chenxi LiuInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Pinghua LiInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Wuduo ZhouInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Xiang MaInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Xiaopeng WangCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Yan XuJiangsu Provincial Station of Animal Husbandry, Nanjing, China.
Nengjing JiangInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Moran ZhaoInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Tianwei ZhouInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Yanzhen YinInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Jun RenCollege of Animal Science, South China Agricultural University, Guangzhou, China.
Ruihua HuangInstitute of Swine Science, Nanjing Agricultural University, Nanjing, China.
Nanjing Agricultural University · CNSouth China Agricultural University · CNJiangsu Agri-animal Husbandry Vocational College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chinese indigenous pig breeds in the Taihu Lake (TL) region of Eastern China are well documented by their exceptional prolificacy. There are seven breeds in this region including Meishan (MS), Erhualian (EHL), Jiaxing Black (JXB), Fengjing (FJ), Shawutou (SWT), Mi (MI), and Hongdenglong (HDL). At present, these breeds are facing a great threat of population decline, inbreeding depression and lineage admixture since Western commercial pigs have dominated in Chinese pig industry. To provide better conservation strategies and identify candidate genes under selection for these breeds, we explored genome-wide single nucleotide polymorphism (SNP) markers to uncover genetic variability and relatedness, population structure, historical admixture and genomic signature of selection of 440 pigs representing the most comprehensive lineages of these breeds in TL region in a context of 1228 pigs from 45 Eurasian breeds. We showed that these breeds were more closely related to each other as compared to other Eurasian breeds, defining one of the main ancestral lineages of Chinese indigenous pigs. These breeds can be divided into two subgroups, one including JXB and FJ, and the other comprising of EHL, MI, HDL, MS, and SWT. In addition, HDL was highly inbred whereas EHL and MS had more abundant genetic diversity owing to their multiple conservation populations. Moreover, we identified a list of candidate genes under selection for body size and prolificacy. Our results would benefit the conservation of these valuable breeds and improve our understanding of the genetic mechanisms of body size and fecundity in pigs.

Indexed as

candidate geneconservation statushistorical relatednessindigenous pigTaihu Lake region

Identifiers

PMID32582299
PMCPMC7296076
OpenAlexW3034255283

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.