ReviewFrontiers in genetics2020
Enzymatic Functions for Toll/Interleukin-1 Receptor Domain Proteins in the Plant Immune System.
Review in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 55 citations in OpenAlex.
- TheProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Exploring a Role for the Arabidopsis TIR-X Gene (TIRP) in the Defense Against Pathogenic Fungi or Insect Herbivory Attack.International journal of molecular sciences · 2025Article
- Deciphering Plant NLR Genomic Evolution: Synteny-Informed Classification Unveils Insights into TNL Gene Loss.Molecular biology and evolution · 2025Article
- Cullin-Conciliated Regulation of Plant Immune Responses: Implications for Sustainable Crop Protection.Plants (Basel, Switzerland) · 2024Review
- The soybean plasma membrane GmDR1 protein conferring broad-spectrum disease and pest resistance regulates several receptor kinases and NLR proteins.Scientific reports · 2024Article
- Toll/interleukin-1 receptor (TIR) domain-containing proteins have NAD-RNA decapping activity.Nature communications · 2024Article
- Jurassic NLR: Conserved and dynamic evolutionary features of the atypically ancient immune receptor ZAR1.The Plant cell · 2023Article
- Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products.Science advances · 2023Article
- Article
- Molecular innovations in plant TIR-based immunity signaling.The Plant cell · 2022Review
- A phytobacterial TIR domain effector manipulates NADThe New phytologist · 2022Article
- Calcium channels and transporters: Roles in response to biotic and abiotic stresses.Frontiers in plant science · 2022Review
- Article
- How activated NLRs induce anti-microbial defenses in plants.Biochemical Society transactions · 2021Review
- Recent Advances in Effector-Triggered Immunity in Plants: New Pieces in the Puzzle Create a Different Paradigm.International journal of molecular sciences · 2021Review
- Overexpression of Salicylic Acid Carboxyl Methyltransferase (International journal of molecular sciences · 2021Article
- Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ.Science (New York, N.Y.) · 2020Article
- Advancement of research on plant NLRs evolution, biochemical activity, structural association, and engineering.Planta · 2020Review
- Reinventing the wheel with a synthetic plant inflammasome.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rationally engineered improvements to crop plants will be needed to keep pace with increasing demands placed on agricultural systems by population growth and climate change. Engineering of plant immune systems provides an opportunity to increase yields by limiting losses to pathogens. Intracellular immune receptors are commonly used as agricultural disease resistance traits. Despite their importance, how intracellular immune receptors confer disease resistance is still unknown. One major class of immune receptors in dicots contains a Toll/Interleukin-1 Receptor (TIR) domain. The mechanisms of TIR-containing proteins during plant immunity have remained elusive. The TIR domain is an ancient module found in archaeal, bacterial and eukaryotic proteins. In animals, TIR domains serve a structural role by generating innate immune signaling complexes. The unusual animal TIR-protein, SARM1, was recently discovered to function instead as an enzyme that depletes cellular NAD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.