ArticleFrontiers in microbiology2020
Growth and Break-Up of Methanogenic Granules Suggests Mechanisms for Biofilm and Community Development.
Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 31 citations in OpenAlex.
- Size matters: Anaerobic granules exhibit distinct ecological and physico-chemical gradients across biofilm size.Environmental science and ecotechnology · 2025Article
- Identifying microbial functional guilds performing cryptic organotrophic and lithotrophic redox cycles in anaerobic granular biofilms.PloS one · 2025Article
- Biofilm application for anaerobic digestion: a systematic review and an industrial scale case.Biotechnology for biofuels and bioproducts · 2024Review
- Mechanisms of microbial co-aggregation in mixed anaerobic cultures.Applied microbiology and biotechnology · 2024Review
- First evidence for temperature's influence on the enrichment, assembly, and activity of polyhydroxyalkanoate-synthesizing mixed microbial communities.Frontiers in systems biology · 2024Article
- Unifying concepts in methanogenic, aerobic, and anammox sludge granulation.Environmental science and ecotechnology · 2024Review
- Trophic interactions shape the spatial organization of medium-chain carboxylic acid producing granular biofilm communities.The ISME journal · 2023Article
- Elucidating the Role of Biofilm-Forming Microbial Communities in Fermentative Biohydrogen Process: An Overview.Microorganisms · 2022Review
- A Distinct, Flocculent, Acidogenic Microbial Community Accompanies Methanogenic Granules in Anaerobic Digesters.Microbiology spectrum · 2021Article
- Multiscale Modelling of De Novo Anaerobic Granulation.Bulletin of mathematical biology · 2021Article
- Size Shapes the Active Microbiome of Methanogenic Granules, Corroborating a Biofilm Life Cycle.mSystems · 2020Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Methanogenic sludge granules are densely packed, small, spherical biofilms found in anaerobic digesters used to treat industrial wastewaters, where they underpin efficient organic waste conversion and biogas production. Each granule theoretically houses representative microorganisms from all of the trophic groups implicated in the successive and interdependent reactions of the anaerobic digestion (AD) process. Information on exactly how methanogenic granules develop, and their eventual fate will be important for precision management of environmental biotechnologies. Granules from a full-scale bioreactor were size-separated into small (0.6-1 mm), medium (1-1.4 mm), and large (1.4-1.8 mm) size fractions. Twelve laboratory-scale bioreactors were operated using either small, medium, or large granules, or unfractionated sludge. After >50 days of operation, the granule size distribution in each of the small, medium, and large bioreactor sets had diversified beyond-to both bigger and smaller than-the size fraction used for inoculation. Interestingly, extra-small (XS; <0.6 mm) granules were observed, and retained in all of the bioreactors, suggesting the continuous nature of granulation, and/or the breakage of larger granules into XS bits. Moreover, evidence suggested that even granules with small diameters could break. "New" granules from each emerging size were analyzed by studying community structure based on high-throughput 16S rRNA gene sequencing.
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Registered trials
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