ArticleFrontiers in microbiology2020
Insight Into the Effects of Nisin and Cecropin on the Oral Microbial Community of Rats by High-Throughput Sequencing.
Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- In vitro study on the bacteriostatic effect of Amoxicillin-loaded Nano-hydroxyapatite and its capability in occluding dentinal tubules.Scientific reports · 2025Article
- Oral microbiota: Roles and treatment in radiation injury (Review).Oncology letters · 2025Review
- Comprehensive Review on the Biocontrol ofFoods (Basel, Switzerland) · 2024Review
- Use of non-canonical amino acids in genetic code expansion-based therapeutics: Effects on mouse gut microbiota.Microbial biotechnology · 2023Article
- Nisin probiotic prevents inflammatory bone loss while promoting reparative proliferation and a healthy microbiome.NPJ biofilms and microbiomes · 2022Article
- Antimicrobial peptides: Defending the mucosal epithelial barrier.Frontiers in oral health · 2022Review
- Oral Administration of 5-Hydroxytryptophan Restores Gut Microbiota Dysbiosis in a Mouse Model of Depression.Frontiers in microbiology · 2022Article
- Influence of the dental topical application of a nisin-biogel in the oral microbiome of dogs: a pilot study.PeerJ · 2021Article
- Effects of Nisin, Cecropin, andFrontiers in nutrition · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oral microbiome has major impacts on oral health and disease. Antimicrobial peptides (AMPs), such as nisin and cecropin, have been widely used as food preservatives or feed additives, and are thus inevitably ingested by consumers through their oral cavity. However, as broad-spectrum antimicrobial reagents, the effect of AMPs on the oral microbiome of consumer's remains poorly characterized. In this study, we performed 16S rDNA high-throughput sequencing to investigate the effect of nisin and cecropin on the oral microbiomes of rats. Our results suggest that although nisin and cecropin have different effects on the oral microbiome of rats, both AMPs impact the composition of oral microbial communities at the phylum and genus levels. Cecropin significantly reduced the diversity and richness of rat oral microbial communities. Notably, the relative abundance of the pathogen
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Registered trials
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