ReviewFrontiers in pharmacology2020
Microscopic Authentication of Commercial Herbal Products in the Globalized Market: Potential and Limitations.
Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Authentication ofFrontiers in pharmacology · 2022Pooled it
- Article
- Integrated ITS2 DNA Barcoding and LC-QTOF/MS Metabolomics for Authentication of Ngueak Pla Mo (Plants (Basel, Switzerland) · 2026Article
- Cultivar to chemotype: characterizing complex botanicals with mass spectrometry metabolomics.Natural product reports · 2026Review
- From fragmented innovation to an integrated plant-to-product framework: integrated digital twins and artificial intelligence approaches in phytomedicine.Frontiers in pharmacology · 2026Article
- Quality Control Strategies for Differentiation of Kalanchoe Species.Phytochemical analysis : PCA · 2025Article
- An effective microscopic image augmentation approach.Scientific reports · 2025Article
- Sustainable cultivation of phytopharmaceuticals in Baden-Wuerttemberg, Germany: a SWOT analysis and future directions.Pharmaceutical biology · 2025Article
- Integrating DNA Barcoding Within an Orthogonal Approach for Herbal Product Authentication: A Narrative Review.Phytochemical analysis : PCA · 2025Review
- Flavonoids and Other Polyphenols: Bioactive Molecules from Traditional Medicine Recipes/Medicinal Plants and Their Potential for Phytopharmaceutical and Medical Application.Molecules (Basel, Switzerland) · 2024Review
- Monitoring Indian "Superfood" Moringa oleifera Lam. - species-specific PCR-fingerprint-based authentication for more consumer safety.NPJ science of food · 2024Article
- A segmentation-combination data augmentation strategy and dual attention mechanism for accurate Chinese herbal medicine microscopic identification.Frontiers in plant science · 2024Article
- Current use of medicinal plants for children's diseases among mothers in Southern Romania.Frontiers in pharmacology · 2024Article
- Horizon scan of DNA-based methods for quality control and monitoring of herbal preparations.Frontiers in pharmacology · 2023Review
- Risk of Poisoning from Garden Plants: Misidentification between Laurel and Cherry Laurel.Toxins · 2022Article
- In Vitro and In Vivo Antidiabetic Activity, Phenolic Content and Microscopical Characterization ofMolecules (Basel, Switzerland) · 2022Article
- Advancements and future prospective of DNA barcodes in the herbal drug industry.Frontiers in pharmacology · 2022Review
- DNA Barcode Authentication of Devil's Claw Herbal Dietary Supplements.Plants (Basel, Switzerland) · 2021Article
- Potential Risks of Plant Constituents in Dietary Supplements: Qualitative and Quantitative Analysis ofMolecules (Basel, Switzerland) · 2021Article
- The efficacy of machine learning algorithm for raw drug authentication inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herbal products are marketed and used around the globe for their claimed or expected health benefits, but their increasing demand has resulted in a proportionally increase of their accidental contamination or intentional adulteration, as already confirmed with DNA-based methods. Microscopy is a traditional pharmacopoeial method used for plant identification and we systematically searched for peer-reviewed publications to document its potential and limitations to authenticate herbal medicines and food supplements commercially available on the global market. The overall authenticity of 508 microscopically authenticated herbal products, sold in 13 countries, was 59%, while the rest of 41% were found to be adulterated. This problem was extending over all continents. At the national level, there were conspicuous differences, even between neighboring countries. These microscopically authenticated commercial herbal products confirm that different magnifying instruments can be used to authenticate crude or processed herbal products traded in the global marketplace. The reviewed publications report the successful use of different magnifying instruments, single or in combinations with a second one, with or without a chemical or DNA-based technique. Microscopy is therefore a rapid and cost-efficient method, and can cope with mixtures and impurities. However, it has limited applicability for highly processed samples. Microscopic authentication of commercial herbal products will therefore contribute to raise public awareness for the extent of adulteration and the need to safeguard consumer safety against the challenges of globalization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.