Evidence map›Paper›PMID 32581768›Full record

ArticleFrontiers in aging neuroscience2020

Enriching Hippocampal Memory Function in Older Adults Through Real-World Exploration.

Branden S Kolarik, Shauna M Stark, Craig E L Stark

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Neurosustainability.Frontiers in human neuroscience · 2024
    Article
  5. Article
  6. Article
  7. Effects of acute aerobic exercise on mnemonic discrimination performance in older adults.Journal of the International Neuropsychological Society : JINS · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Change Is Good for the Brain: Activity Diversity and Cognitive Functioning Across Adulthood.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
  12. Article
  13. PlayingFrontiers in sports and active living · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Branden S KolarikDepartment of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, United States.
Shauna M StarkDepartment of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, United States.
Craig E L StarkDepartment of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, United States.

Funding

High-resolution Structural and Functional Brain Imaging of the Medial Temporal LoR01AG034613 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI STARK, CRAIG E · 2009 to 2018
$4.6M
Videogame-based environmental enrichment training for altercations in hippocampal function and memory in middle-aged adultsR21AG056145 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI STARK, CRAIG E · 2017 to 2018
$425k
NIA NIH HHS R01 AG034613NIA NIH HHS R21 AG056145
6 · The paper itself

Abstract

Age-related structural and functional changes in the hippocampus can have a severe impact on hippocampal-dependent memory performance. Here, we tested the hypothesis that a real-world spatial exploration and learning intervention would improve hippocampal-dependent memory performance in healthy older adults. We developed a scavenger hunt task that participants performed over the course of a 4-week behavioral intervention period. Following this intervention, participants' lure discrimination index (LDI) on the Mnemonic Similarity Task was significantly higher than it was at baseline and greater than that of a No-Contact Control Group, while traditional recognition scores remained relatively unchanged. These results point to the viability of a spatial exploration intervention for improving hippocampal-dependent memory in older adults.

Indexed as

agingenvironmental enrichmentinterventionpattern separationspatial exploration

Identifiers

PMID32581768
PMCPMC7286388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.