ArticleClinical interventions in aging2020
Simplifying Medication Regimens for People Receiving Community-Based Home Care Services: Outcomes of a Non-Randomized Pilot and Feasibility Study.
Article in Clinical interventions in aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Process Evaluation of the SImplification of Medications Prescribed to Long-tErm Care Residents (SIMPLER) Cluster Randomized Controlled Trial: A Mixed Methods Study.International journal of environmental research and public health · 2021Trial
- Global Trends and Research Hot Spots in Medication Regimen Simplification: Bibliometric Analysis.JMIR aging · 2026Article
- Nurse Practitioner-Pharmacist Collaboration for Medication Regimen Simplification: Pilot and Feasibility Study of a New Telehealth Model of Care.Journal of nursing management · 2026Article
- The role and perception of the caregiver in a specialized pediatric palliative care center in medicine preparation and administration: a survey study.Italian journal of pediatrics · 2024Article
- Unravelling the shift: exploring consumers' adoption or resistance of E-Pharmacy through behavioural reasoning theory.BMC public health · 2024Article
- Polypharmacy in Children with Medical Complexity: A Cross-Sectional Study in a Pediatric Palliative Care Center.Children (Basel, Switzerland) · 2024Article
- Tools to measure barriers to medication management capacity in older adults: a scoping review.BMC geriatrics · 2024Article
- Article
- Complexity of Medication Regimens for Children With Neurological Impairment.JAMA network open · 2021Article
- Impact of Medication Regimen Simplification on Medication Incidents in Residential Aged Care: SIMPLER Randomized Controlled Trial.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeBeing able to manage a complex medication regimen is key to older people continuing to live at home. This study determined the feasibility of a multi-component intervention to simplify medication regimens for people receiving community-based home care services. PATIENTS AND
methodsResearch nurses recruited people receiving community-based home care services to participate in this non-randomized pilot and feasibility study (Australian New Zealand Clinical Trials Registry ACTRN12618001130257). Participants received a one-off clinical pharmacist intervention comprising medication reconciliation, assessment of capacity to self-manage medications, and application of a structured 5-step tool to identify medication simplification opportunities. A mixed-methods feasibility assessment with an explanatory design was undertaken to assess recruitment, protocol adherence and stakeholder acceptability. Data from interviews with 12 stakeholders were thematically analyzed. Secondary outcome measures, including medication discrepancies, and changes in number of medication administration times per day, quality of life, medication adherence and health service utilization, were determined over a 4-month follow-up.
resultsTwenty-five out of the target 50 participants were recruited. Initial recruitment was impacted by apparent uncertain role responsibilities in medication management, with some clients who declined to participate perceiving they would be unlikely to benefit or being reluctant to change regimens. However, with few exceptions, participants who received intervention did so with a high degree of protocol adherence and acceptability. Stakeholders valued the intervention and supported wider implementation. Discrepancies between the baseline medication history from the general medical practitioner and the pharmacist-compiled "best possible medication history" were identified for all participants' regimens (median of 6 per participant), with one-third resolved at follow-up. Simplification was possible for 14 participants (56%) and implemented for 7 (50%) at follow-up. No significant changes in other secondary outcomes were observed.
conclusionThe intervention was delivered as planned, and valued by stakeholders. Recruitment barriers should be addressed before wider implementation.
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