Evidence map›Paper›PMID 32581406›Full record

ArticleNagoya journal of medical science2020

Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes.

Chisato Inoue, Sayaka Sobue, Naoki Mizutani, Yoshiyuki Kawamoto, Yuji Nishizawa, Masatoshi Ichihara, Toshiyuki Takeuchi, Fumihiko Hayakawa, Motoshi Suzuki, Tetsuro Ito and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nagoya journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Chisato InoueCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Sayaka SobueCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Naoki MizutaniCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Yoshiyuki KawamotoCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Yuji NishizawaCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Masatoshi IchiharaCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Toshiyuki TakeuchiDepartment of Molecular Oncology, Fujita Health University, Toyoake, Japan.
Fumihiko HayakawaDepartment of Medical Technology, Nagoya University Graduate School of Health Sciences, Nagoya, Japan.
Motoshi SuzukiDepartment of Molecular Oncology, Fujita Health University, Toyoake, Japan.
Tetsuro ItoGifu Pharmaceutical University, Gifu, Japan.
Yoshinori NozawaTokai Gakuin University, Kakamigahara, Japan.
Takashi MurateCollege of Life and Health Sciences, Chubu University, Kasugai, Japan.
Chubu University · JPFujita Health University · JPGifu Pharmaceutical University · JPNagoya City University · JPTokai Gakuin University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resveratrol (RSV) has recently attracted keen interest because of its pleiotropic effects. It exerts a wide range of health-promoting effects. In addition to health-promoting effects, RSV possesses anti-carcinogenic activity. However, a non-physiological concentration is needed to achieve an anti-cancer effect, and its

Indexed as

Amino Acid Chloromethyl KetonesAntioxidantsApoptosisCaspase InhibitorsCell Line, TumorCell ProliferationCell SurvivalDrug Resistance, NeoplasmGlucosyltransferasesHumansInhibitory Concentration 50Jurkat CellsK562 CellsPC-3 CellsPhosphotransferases (Alcohol Group Acceptor)ResveratrolAmino Acid Chloromethyl KetonesAntioxidantsbenzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketoneCaspase Inhibitorsceramide glucosyltransferaseGlucosyltransferasesPhosphotransferases (Alcohol Group Acceptor)ResveratrolSphingosine Kinasesphingosine kinase 2, humanStilbenesvaticanol CapoptosisGCSsphingolipid rheostatSPHKvaticanol C

Identifiers

PMID32581406
PMCPMC7276413
OpenAlexW2997712761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.