ArticleScientific reports2020
Northern and southern blacklegged (deer) ticks are genetically distinct with different histories and Lyme spirochete infection rates.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- When Clades Collide: Genomic Admixture in Blacklegged Ticks (Ixodes scapularis) From the Great Plains.Molecular ecology · 2026Article
- Contrasting epigenetics of Ixodes scapularis populations.Scientific reports · 2026Article
- It takes a village: Community science informs tick encounter, pathogen, and exposure risk in North Carolina, USA.PloS one · 2026Article
- Genetic and Landscape Connectivity of Blacklegged Ticks During Range Expansion in Select States of the Midwestern USA.Ecology and evolution · 2025Article
- Update on North American tick-borne diseases and how to diagnose them.Journal of clinical microbiology · 2025Review
- Estimating the density of questing Ixodes scapularis nymphs in the eastern United States using climate and land cover data.Ticks and tick-borne diseases · 2025Article
- Whole Genome Sequencing Reveals Clade-Specific Genetic Variation in Blacklegged Ticks.Ecology and evolution · 2025Article
- Lizards and the enzootic cycle of Borrelia burgdorferi sensu lato.Molecular microbiology · 2024Review
- Article
- Changes in the geographic distribution of the blacklegged tick, Ixodes scapularis, in the United States.Ticks and tick-borne diseases · 2023Review
- Prevalence of five human pathogens in host-seeking Ixodes scapularis and Ixodes pacificus by region, state, and county in the contiguous United States generated through national tick surveillance.Ticks and tick-borne diseases · 2023Article
- Prevalence of Borrelia burgdorferi and diversity of its outer surface protein C (ospC) alleles in blacklegged ticks (Ixodes scapularis) in Delaware.Ticks and tick-borne diseases · 2023Article
- Risky business: human-related data is lacking from Lyme disease risk models.Frontiers in public health · 2023Review
- Phylodynamics of deer tick virus in North America.Virus evolution · 2023Article
- Automatic barcode gap discovery reveals diverse clades of Rhipicephalus spp. and Haemaphysalis spp. ticks from small mammals in 'Asir, Saudi Arabia.Parasites & vectors · 2021Article
- Reptile Host Associations ofPathogens (Basel, Switzerland) · 2021Article
- Possible Effects of Climate Change on Ixodid Ticks and the Pathogens They Transmit: Predictions and Observations.Journal of medical entomology · 2021Article
- Perpetuation of Borreliae.Current issues in molecular biology · 2021Article
- Why Lyme disease is common in the northern US, but rare in the south: The roles of host choice, host-seeking behavior, and tick density.PLoS biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lyme borreliosis (LB) is the archetypal emerging zoonosis and is dependent on transmission by ticks in the genus Ixodes. Understanding the origin, maintenance, and spread of these ticks contributes much to our understanding of the spread of LB and other disease agents borne by these ticks. We collected 1232 Ixodes scapularis ticks from 17 east coast sites ranging from New Hampshire to Florida and used mtDNA, three nuclear genetic loci, and incorporated Bayesian analyses to resolve geographically distinct tick populations and compare their demographic histories. A sparse, stable, and genetically diverse population of ticks in the Southeastern US, that is rarely infected with the agent of LB is genetically distinct from an abundant, expanding, and comparatively uniform population in the Northeast, where epidemic LB now constitutes the most important vector borne disease in the United States. The contrasting geography and demography of tick populations, interpreted in the context of the geological history of the region, suggests that during the last glacial period such ticks occupied distinct refugia, with only the northern-most site of refuge giving rise to those ticks and pathogens now fueling the epidemic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.