Evidence map›Paper›PMID 32581091›Full record

ArticleJournal of virology2020

The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9.

Yuma Nagano, Aoi Sugiyama, Madoka Kimoto, Takuya Wakahara, Yasuyo Noguchi, Xinxin Jiang, Shinya Saijo, Nobutaka Shimizu, Nana Yabuno, Min Yao and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Yuma NaganoFaculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Aoi SugiyamaFaculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Madoka KimotoFaculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Takuya WakaharaFaculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Yasuyo NoguchiFaculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Xinxin JiangFaculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Shinya SaijoPhoton Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Japan.
Nobutaka ShimizuPhoton Factory, Institute of Materials Structure Science, High Energy Accelerator Research Organization (KEK), Tsukuba, Japan.
Nana YabunoFaculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Min YaoFaculty of Advanced Life Science, Hokkaido University, Sapporo, Japan.
Paul R GooleyDepartment of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Victoria, Australia.
Gregory W MoseleyDepartment of Microbiology, Biomedicine Discovery Institute, Monash University, Victoria, Australia.
Takashi TadokoroFaculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Katsumi MaenakaFaculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Toyoyuki OseFaculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan ose.toyoyuki@sci.hokudai.ac.jp.ORCID 0000-0002-2001-9388
Hokkaido University · JPHigh Energy Accelerator Research Organization · JPAustralian Regenerative Medicine Institute · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measles virus (MeV) is a highly immunotropic and contagious pathogen that can even diminish preexisting antibodies and remains a major cause of childhood morbidity and mortality worldwide despite the availability of effective vaccines. MeV is one of the most extensively studied viruses with respect to the mechanisms of JAK-STAT antagonism. Of the three proteins translated from the MeV

Indexed as

Binding SitesGene ExpressionHumansImmune EvasionImmunity, InnateInterferon-Stimulated Gene Factor 3, gamma SubunitJanus KinasesMeasles virusPhosphoproteinsProtein BindingProtein DomainsProtein Interaction Domains and MotifsSignal TransductionSTAT1 Transcription FactorSTAT2 Transcription FactorViral ProteinsInterferon-Stimulated Gene Factor 3, gamma SubunitIRF9 protein, humanJanus KinasesPhosphoproteinsSTAT1 protein, humanSTAT1 Transcription FactorSTAT2 protein, humanSTAT2 Transcription FactorViral ProteinsV protein, measles virusimmune evasioninnate immunitymeaslesparamyxovirusprotein-protein interactionsprotein purificationrecombinant-protein productionSTAT transcription factorsstructural biologyzinc finger proteins

Identifiers

PMID32581091
PMCPMC7431810
OpenAlexW3037404617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.