Evidence map›Paper›PMID 32580520›Full record

ArticleGenes2020

Novel Insights into the Protective Properties of ACTH

Ivan B Filippenkov, Vasily V Stavchansky, Alina E Denisova, Vadim V Yuzhakov, Larisa E Sevan'kaeva, Olga Y Sudarkina, Veronika G Dmitrieva, Leonid V Gubsky, Nikolai F Myasoedov, Svetlana A Limborska and 1 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

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  19. Brain Protein Expression Profile Confirms the Protective Effect of the ACTHInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ivan B FilippenkovInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Vasily V StavchanskyInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Alina E DenisovaPirogov Russian National Research Medical University, Federal Center of Cerebrovascular Pathology and Stroke, Ministry of Health Care of Russian Federation, 117342 Moscow, Russia.
Vadim V YuzhakovA. Tsyb Medical Radiological Research Center - branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, 249031 Obninsk, Russia.
Larisa E Sevan'kaevaA. Tsyb Medical Radiological Research Center - branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, 249031 Obninsk, Russia.
Olga Y SudarkinaInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Veronika G DmitrievaInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Leonid V GubskyPirogov Russian National Research Medical University, Federal Center of Cerebrovascular Pathology and Stroke, Ministry of Health Care of Russian Federation, 117342 Moscow, Russia.
Nikolai F MyasoedovInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Svetlana A LimborskaInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Lyudmila V DergunovaInstitute of Molecular Genetics, Russian Academy of Sciences, 123182 Moscow, Russia.
Institute of Molecular Genetics · RUMinistry of Health of the Russian Federation · RUPirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral ischaemia is the most common cause of impaired brain function. Biologically active peptides represent potential drugs for reducing the damage that occurs after ischaemia. The synthetic melanocortin derivative, ACTH

Indexed as

Adrenocorticotropic HormoneAnimalsBrainBrain IschemiaDisease Models, AnimalHumansInfarction, Middle Cerebral ArteryPeptide FragmentsRatsReperfusion InjuryRNA-SeqTranscriptomeACTH (4-7), Pro-Gly-Pro-Adrenocorticotropic HormonePeptide FragmentsmRNA expressionpeptide regulationRNA-Seqsynthetic melanocortin derivative ACTH(4-7)PGP (Semax)tMCAO

Identifiers

PMID32580520
PMCPMC7350263
OpenAlexW3036055014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.