Evidence map›Paper›PMID 32580496›Full record

ArticlePolymers2020

Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing.

Vojtěch Kupka, Eva Dvořáková, Anton Manakhov, Miroslav Michlíček, Josef Petruš, Lucy Vojtová, Lenka Zajíčková

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Vojtěch KupkaCentral European Institute of Technology-CEITEC, Brno University of Technology, Purkyňova 123, 61200 Brno, Czech Republic.
Eva DvořákováCentral European Institute of Technology-CEITEC, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Anton ManakhovCentral European Institute of Technology-CEITEC, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Miroslav MichlíčekCentral European Institute of Technology-CEITEC, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Josef PetrušCentral European Institute of Technology-CEITEC, Brno University of Technology, Purkyňova 123, 61200 Brno, Czech Republic.
Lucy VojtováCentral European Institute of Technology-CEITEC, Brno University of Technology, Purkyňova 123, 61200 Brno, Czech Republic.
Lenka ZajíčkováCentral European Institute of Technology-CEITEC, Brno University of Technology, Purkyňova 123, 61200 Brno, Czech Republic.
Central European Institute of Technology · CZNational University of Science and Technology · RU

Funding

Grantová Agentura České Republiky 18-12774SMinisterstvo Školství, Mládeže a Tělovýchovy CZ.02.1.01/0.0/0.0/16_019/0000754Ministerstvo Školství, Mládeže a Tělovýchovy LM2018110Ministerstvo Školství, Mládeže a Tělovýchovy LQ1601Russian Science Foundation 18-75-10057
6 · The paper itself

Abstract

Biodegradable composite nanofibers were electrospun from poly(ε-caprolactone) (PCL) and poly(ethylene oxide) (PEO) mixtures dissolved in acetic and formic acids. The variation of PCL:PEO concentration in the polymer blend, from 5:95 to 75:25, revealed the tunability of the hydrolytic stability and mechanical properties of the nanofibrous mats. The degradation rate of PCL/PEO nanofibers can be increased compared to pure PCL, and the mechanical properties can be improved compared to pure PEO. Although PCL and PEO have been previously reported as immiscible, the electrospinning into nanofibers having restricted dimensions (250-450 nm) led to a microscopically mixed PCL/PEO blend. However, the hydrolytic stability and tensile tests revealed the segregation of PCL into few-nanometers-thin fibrils in the PEO matrix of each nanofiber. A synergy phenomenon of increased stiffness appeared for the high concentration of PCL in PCL/PEO nanofibrous mats. The pure PCL and PEO mats had a Young's modulus of about 12 MPa, but the mats made of high concentration PCL in PCL/PEO solution exhibited 2.5-fold higher values. The increase in the PEO content led to faster degradation of mats in water and up to a 20-fold decrease in the nanofibers' ductility. The surface of the PCL/PEO nanofibers was functionalized by an amine plasma polymer thin film that is known to increase the hydrophilicity and attach proteins efficiently to the surface. The combination of different PCL/PEO blends and amine plasma polymer coating enabled us to tune the surface functionality, the hydrolytic stability, and the mechanical properties of biodegradable nanofibrous mats.

Indexed as

mechanical propertiesplasma enhanced CVDpolymer fibersSEMthin films

Identifiers

PMID32580496
PMCPMC7362260
OpenAlexW3036403675

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.