ReviewJournal of clinical medicine2020
A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Evaluating the Evidence Base of Melatonin, Light Exposure, Exercise, and Complementary and Alternative Medicine for Patients with Insomnia Disorder.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Effects of different intervention modalities combined with exercise in patients with insomnia: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Pooled it
- Insomnia evaluation and treatment during peripartum: a joint position paper from the European Insomnia Network task force "Sleep and Women," the Italian Marcè Society and international experts task force for perinatal mental health.Archives of women's mental health · 2022Pooled it
- Effects of Exercise on Sleep Quality and Insomnia in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in psychiatry · 2021Pooled it
- Treatment of chronic primary sleep onset insomnia with Kundalini yoga: a randomized controlled trial with active sleep hygiene comparison.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Trial
- Therapeutic prospects of bright light therapy in addictive disorders: a scoping review.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Digital Cognitive Behavioural Therapy for Insomnia Delivered Within a Crenotherapy Setting: Results from a Multicentre Proof-of-Concept Randomised Controlled Trial.Journal of clinical medicine · 2026Article
- Illuminating Insomnia: A Scientometric Exploration of Complementary and Alternative Medicine in Treatment Research.Journal of lifestyle medicine · 2026Review
- Effectiveness of Homoeopathic Treatments for Sleep Disorders in Children and Adolescents: A Systematic Review According to the Principles of Evidence-Based Medicine.Children (Basel, Switzerland) · 2025Review
- [Effects of light therapy on sleep efficiency in older adults in long-term care facilities: a systematic review and meta-analysis].Journal of Korean biological nursing science · 2025Review
- The relationship between perceived organizational support and insomnia in psychiatric nurses in China: the mediating role of psychological capital.BMC nursing · 2025Article
- Innovative Digital Cognitive Behavioral Treatment for Insomnia Disorder in Adults (dCBT-i): Framework Development.JMIR human factors · 2025Article
- Unfolding the role of exercise in the management of sleep disorders.European journal of applied physiology · 2024Review
- Global trend of nondrug and nonsedativehypnotic treatment forinsomnia: a bibliometric study.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Review
- Evaluation and management of insomnia in the clinical practice in Italy: a 2023 update from the Insomnia Expert Consensus Group.Journal of neurology · 2024Review
- Sleep disorders and exercise: a mini-review.Journal of thoracic disease · 2023Review
- 2023 Guidelines on the Diagnosis and Treatment of Insomnia in Adults - Brazilian Sleep Association.Sleep science (Sao Paulo, Brazil) · 2023Review
- Circadian Interventions as Adjunctive Therapies to Cognitive-Behavioral Therapy for Insomnia.Sleep medicine clinics · 2023Review
- Study of the Effects of Melatonin on Sleep Disorders in Pulmonary Sarcoidosis Patients.Iranian journal of pharmaceutical research : IJPR · 2022Article
- Sex Differences Across the Life Course: A Focus On Unique Nutritional and Health Considerations among Women.The Journal of nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
Insomnia is a prevalent disorder and it leads to relevant impairment in health-related quality of life. Recent clinical guidelines pointed out that Cognitive-Behavior Therapy for Insomnia (CBT-I) should be considered as first-line intervention. Nevertheless, many other interventions are commonly used by patients or have been proposed as effective for insomnia. These include melatonin, light exposure, exercise, and complementary and alternative medicine. Evaluation of comparable effectiveness of these interventions with first-line intervention for insomnia is however still lacking. We conducted a systematic review and network meta-analysis on the effects of these interventions. PubMed, PsycInfo, PsycArticles, MEDLINE, and CINAHL were systematically searched and 40 studies were included in the systematic review, while 36 were entered into the meta-analysis. Eight network meta-analyses were conducted. Findings support effectiveness of melatonin in improving sleep-onset difficulties and of meditative movement therapies for self-report sleep efficiency and severity of the insomnia disorder. Some support was observed for exercise, hypnotherapy, and transcranial magnetic resonance, but the number of studies for these interventions is still too small. None of the considered interventions received superior evidence to CBT-I, which should be more widely disseminated in primary care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.