Evidence map›Paper›PMID 32580336›Full record

ArticleInternational journal of molecular sciences2020

Quantitative Near-Infrared Imaging of Platelets in Platelet-Rich Fibrin (PRF) Matrices: Comparative Analysis of Bio-PRF, Leukocyte-Rich PRF, Advanced-PRF and Concentrated Growth Factors.

Hachidai Aizawa, Tetsuhiro Tsujino, Taisuke Watanabe, Kazushige Isobe, Yutaka Kitamura, Atsushi Sato, Sadahiro Yamaguchi, Hajime Okudera, Kazuhiro Okuda, Tomoyuki Kawase

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Advances in Research on Concentrated Growth Factor Applications for Androgenetic Alopecia Treatment: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Relative Centrifugal Force (RCF;International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hachidai AizawaTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.ORCID 0000-0002-8584-6819
Tetsuhiro TsujinoTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.ORCID 0000-0002-3802-8581
Taisuke WatanabeTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.
Kazushige IsobeTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.
Yutaka KitamuraTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.
Atsushi SatoTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.ORCID 0000-0002-1817-6405
Sadahiro YamaguchiTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.
Hajime OkuderaTokyo Plastic Dental Society, Kita-ku, Tokyo 114-0002, Japan.
Kazuhiro OkudaDivision of Periodontology, Institute of Medicine and Dentistry, Niigata University, Niigata 951-8514, Japan.
Tomoyuki KawaseDivision of Oral Bioengineering, Institute of Medicine and Dentistry, Niigata University, Niigata 951-8514, Japan.ORCID 0000-0003-4160-396X
Tokyo Dental College · JPNiigata University · JP

Funding

Japan Society for the Promotion of Science 18K-09595
6 · The paper itself

Abstract

Platelet-rich fibrin (PRF) is a fibrin matrix enriched with platelets. The PRF matrix is thought to form a steep gradient of platelet density around the region corresponding to the buffy coat in anticoagulated blood samples. However, this phenomenon has not yet been proven. To visualize platelet distribution in PRF in a non-invasive manner, we utilized near-infrared (NIR) imaging technology. In this study, four types of PRF matrices, bio-PRF, advanced-PRF (A-PRF), leukocyte-rich PRF (L-PRF), and concentrated growth factors (CGF) were compared. Blood samples collected from healthy, non-smoking volunteers were immediately centrifuged using four different protocols in glass tubes. The fixed PRF matrices were sagittally divided into two equal parts, and subjected to modified immunohistochemical examination. After probing with NIR dye-conjugated secondary antibody, the CD41

Indexed as

AdultAgedBlood PlateletsFemaleFibrinHealthy VolunteersHumansIntercellular Signaling Peptides and ProteinsLeukocytesMaleMiddle AgedMolecular ImagingPlatelet-Rich FibrinSpectroscopy, Near-InfraredFibrinIntercellular Signaling Peptides and Proteinsdistributionnear-infrared imagingplatelet-rich fibrinplatelets

Identifiers

PMID32580336
PMCPMC7352590
OpenAlexW3036935292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.