Evidence map›Paper›PMID 32580291›Full record

ArticleCancers2020

An Anti-PSMA Immunotoxin Reduces Mcl-1 and Bcl2A1 and Specifically Induces in Combination with the BAD-Like BH3 Mimetic ABT-737 Apoptosis in Prostate Cancer Cells.

Anie P Masilamani, Viviane Dettmer-Monaco, Gianni Monaco, Toni Cathomen, Irina Kuckuck, Susanne Schultze-Seemann, Nathalie Huber, Philipp Wolf

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Enhanced cytotoxicity of aFrontiers in pharmacology · 2023
    Article
  10. Article
  11. BH3-mimetics: recent developments in cancer therapy.Journal of experimental & clinical cancer research : CR · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anie P MasilamaniDepartment of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0003-2503-1244
Viviane Dettmer-MonacoFaculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Gianni MonacoFaculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.
Toni CathomenFaculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.ORCID 0000-0002-7757-4630
Irina KuckuckDepartment of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Susanne Schultze-SeemannDepartment of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Nathalie HuberDepartment of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
Philipp WolfDepartment of Urology, Medical Center-University of Freiburg, 79106 Freiburg, Germany.
University of Freiburg · DE

Funding

Wilhelm Sander-Stiftung 2016.089.01
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ABT-737apoptosisBcl-2 proteinscombination therapyimmunotoxinprostate cancerPSMAtargeted therapy

Identifiers

PMID32580291
PMCPMC7352695
OpenAlexW3036714594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.