Evidence map›Paper›PMID 32580208›Full record

ArticleNature2020

Structures of metabotropic GABA

Makaía M Papasergi-Scott, Michael J Robertson, Alpay B Seven, Ouliana Panova, Jesper M Mathiesen, Georgios Skiniotis

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 122 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. GPCR Heterodimers: Implications for Biased Signaling.Handbook of experimental pharmacology · 2026
    Review
  6. Article
  7. Review
  8. GABA-independent activation of GABANature communications · 2025
    Article
  9. Article
  10. Structural Basis of GABAAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Molecular regulation of calcium-sensing receptor (CaSR)-mediated signaling.Chronic diseases and translational medicine · 2024
    Review
  20. Impact of aging on the GABAbioRxiv : the preprint server for biology · 2024
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Makaía M Papasergi-Scott *Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3238-3213
Michael J Robertson *Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-2610-680X
Alpay B SevenDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Ouliana PanovaDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.
Jesper M MathiesenDepartment of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-4251-4416
Georgios SkiniotisDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA. yiorgo@stanford.edu.ORCID http://orcid.org/0000-0003-0238-7846
Stanford University · USStanford Medicine · USUniversity of Copenhagen · DK

Funding

Structural Basis of Signal Instigation Through Metabotropic Glutamate ReceptorsR01NS092695 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SKINIOTIS, GEORGIOS · 2015 to 2019
$3.4M
NINDS NIH HHS R01 NS092695
6 · The paper itself

Abstract

Stimulation of the metabotropic GABA

Indexed as

Cryoelectron MicroscopyBinding SitesCell MembraneGABA-B Receptor AntagonistsHumansHydrophobic and Hydrophilic InteractionsLigandsModels, MolecularPhospholipidsProtein DomainsProtein MultimerizationProtein SubunitsReceptors, GABA-BReceptors, GlutamateSignal TransductionStructure-Activity RelationshipGABA-B Receptor AntagonistsLigandsPhospholipidsProtein SubunitsReceptors, GABA-BReceptors, Glutamate

Identifiers

PMID32580208
PMCPMC7429364
OpenAlexW3037829040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.