Evidence map›Paper›PMID 32579864›Full record

ArticleAdipocyte2020

A new human adipocyte model with PTEN haploinsufficiency.

Franziska Kässner, Anna Kirstein, Norman Händel, Gordian L Schmid, Kathrin Landgraf, Antje Berthold, Astrid Tannert, Michael Schaefer, Martin Wabitsch, Wieland Kiess and 2 more

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Franziska KässnerHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.
Anna KirsteinHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.
Norman HändelSt. Georg Hospital , Leipzig, Germany.
Gordian L SchmidDepartment for General Practise, Medical Faculty, Leipzig University , Leipzig, Germany.ORCID 0000-0002-8238-3302
Kathrin LandgrafHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.
Antje BertholdHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.
Astrid TannertLeibniz Institute of Photonic Technology , Jena, Germany.ORCID 0000-0003-4115-2564
Michael SchaeferRudolf Boehm Institute for Pharmacology and Toxicology, Medical Faculty, Leipzig University , Leipzig, Germany.
Martin WabitschDivision of Pediatric Endocrinology and Diabetes, University Hospital for Children and Adolescents, Ulm University , Germany.
Wieland KiessHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.
Antje KörnerHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.ORCID 0000-0001-6001-0356
Antje GartenHospital for Children & Adolescents, Center for Pediatric Research, Leipzig University , Leipzig, Germany.ORCID 0000-0002-5354-287X
Leipzig University · DEKlinikum St. Georg · DELeibniz Institute of Photonic Technology · DEUniversity Hospital Ulm · DEUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few human cell strains are suitable and readily available as

Indexed as

HaploinsufficiencyAdipocytesAdipogenesisAdipose Tissue, WhiteBiomarkersCell DifferentiationCells, CulturedGene Expression RegulationHumansLipid MetabolismLipomaPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseSignal TransductionBiomarkersPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktPTEN PhosphohydrolasePTEN protein, human3D cultureadipocyte differentiationAKTcellular life-spanLipomaphosphatasesphosphoinositide-3-kinaseSGBS

Identifiers

PMID32579864
PMCPMC7469440
OpenAlexW3037412568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.