Evidence map›Paper›PMID 32579860›Full record

ArticleAdipocyte2020

The effect of Acot2 overexpression or downregulation on the preadipocyte differentiation in Chinese Red Steppe cattle.

Lixiang Liu, Jian Wu, Yi Gao, Yang Lv, Jiajia Xue, Lihong Qin, Cheng Xiao, Zhongchang Hu, Lichun Zhang, Xiaotong Luo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Adipocyte, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Lixiang LiuBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Jian WuBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Yi GaoBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Yang LvBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Jiajia XueBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Lihong QinBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Cheng XiaoBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Zhongchang HuBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.ORCID 0000-0002-9855-3134
Lichun ZhangBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Xiaotong LuoBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Yanli WangBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Yang CaoBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Yang CaoBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.ORCID 0000-0002-8910-9576
Guoliang ZhangBranch of Animal Husbandry, Jilin Academy of Agricultural Science , Gongzhuling, China.
Jilin Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quality and nutritional value of beef is closely linked to its content of intramuscular fat (IMF). The differentiation of preadipocytes and the deposition of lipid droplets in the adipocytes are the key to regulate the IMF content. The differentiation of adipocytes is regulated by a series of transcription factors and genes. Acyl-CoA thioesterase 2 (Acot2) hydrolyzes the acyl-coenzyme A (CoA) into free fatty acids and CoA and has the potential to maintain the free fatty acids and acyl CoA at the cellular level. In this work, we detected the expression of the

Indexed as

Gene ExpressionAdipocytesAdipogenesisAnimalsCattleCell DifferentiationCells, CulturedLipid MetabolismRNA InterferenceRNA, Small InterferingThiolester HydrolasesRNA, Small InterferingThiolester HydrolasesAcot2adipocyte differentiationinterferenceoverexpression

Identifiers

PMID32579860
PMCPMC7469445
OpenAlexW3037188063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.