Evidence map›Paper›PMID 32579757›Full record

ArticleDepression and anxiety2020

Neurocognitive predictors of self-reported reward responsivity and approach motivation in depression: A data-driven approach.

Kean J Hsu, Mary E McNamara, Jason Shumake, Rochelle A Stewart, Jocelyn Labrada, Alexandra Alario, Guadalupe D S Gonzalez, David M Schnyer, Christopher G Beevers

Abstract read
In one paragraph

Article in Depression and anxiety, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kean J HsuDepartment of Psychiatry, Georgetown University Medical Center, Washington, DC.ORCID 0000-0001-6192-4045
Mary E McNamaraInstitute for Mental Health Research and Department of Psychology, University of Texas at Austin, Austin, Texas.
Jason ShumakeInstitute for Mental Health Research and Department of Psychology, University of Texas at Austin, Austin, Texas.
Rochelle A StewartDepartment of Psychology, Florida State University, Tallahassee, Florida.
Jocelyn LabradaInstitute for Mental Health Research and Department of Psychology, University of Texas at Austin, Austin, Texas.
Alexandra AlarioInterdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, Iowa.
Guadalupe D S GonzalezInstitute for Mental Health Research and Department of Psychology, University of Texas at Austin, Austin, Texas.
David M SchnyerInstitute for Mental Health Research and Department of Psychology, University of Texas at Austin, Austin, Texas.
Christopher G BeeversInstitute for Mental Health Research and Department of Psychology, University of Texas at Austin, Austin, Texas.

Funding

Dynamics of Inflammation and its Blockade on Motivational Circuitry in DepressionR01MH108605 · NIMH · EMORY UNIVERSITY · PI TREADWAY, MICHAEL TILGHMAN · 2016 to 2020
$2.1M
Development of Attention Bias Modification for DepressionR33MH109600 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI BEEVERS, CHRISTOPHER G, SCHNYER, DAVID M · 2017 to 2019
$2.0M
A computational neuroscience approach to frontal compensation in decision-makingR01AG043425 · NIA · UNIVERSITY OF TEXAS AT AUSTIN · PI SCHNYER, DAVID M, WORTHY, DARRELL A. · 2014 to 2019
$1.7M
Contribution of Genome-Wide Variation to Cognitive Vulnerability to DepressionR56MH108650 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI ALLEN, JOHN J., BEEVERS, CHRISTOPHER G · 2016 to 2016
$767k
Perceptual and decisional processes underlying face perception biases in clinical depressionR21MH112013 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI BEEVERS, CHRISTOPHER G, SOTO, FABIAN A · 2017 to 2018
$429k
NIA NIH HHS AG 043425NIA NIH HHS R01 AG043425NIMH NIH HHS MH108650NIMH NIH HHS MH109600NIMH NIH HHS MH112013NIMH NIH HHS R01 MH108605NIMH NIH HHS R21 MH112013NIMH NIH HHS R33 MH109600NIMH NIH HHS R56 MH108650
6 · The paper itself

Abstract

backgroundIndividual differences in reward-related processes, such as reward responsivity and approach motivation, appear to play a role in the nature and course of depression. Prior work suggests that cognitive biases for valenced information may contribute to these reward processes. Yet there is little work examining how biased attention, processing, and memory for positively and negatively valenced information may be associated with reward-related processes in samples with depression symptoms.

methodsWe used a data-driven, machine learning (elastic net) approach to identify the best predictors of self-reported reward-related processes using multiple tasks of attention, processing, and memory for valenced information measured across behavioral, eye tracking, psychophysiological, and computational modeling approaches (n = 202). Participants were adults (ages 18-35) who ranged in depression symptom severity from mild to severe.

resultsModels predicted between 5.0-12.2% and 9.7-28.0% of held-out test sample variance in approach motivation and reward responsivity, respectively. Low self-referential processing of positively valenced information was the most robust, albeit modest, predictor of low approach motivation and reward responsivity.

conclusionsSelf-referential processing of positive information is the strongest predictor of reward responsivity and approach motivation in a sample ranging from mild to severe depression symptom severity. Experiments are now needed to clarify the causal relationship between self-referential processing of positively valenced information and reward processes in depression.

Indexed as

DepressionMotivationAdolescentAdultAttentionHumansRewardSelf ReportYoung Adultattentional biasbehavioral activation systemcognitive processingdepressionmachine learningmemory

Identifiers

PMID32579757
PMCPMC7951991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.