Evidence map›Paper›PMID 32579702›Full record

ArticleBritish journal of pharmacology2020

Sensitization of glutamate receptor-mediated pain behaviour via nerve growth factor-dependent phosphorylation of transient receptor potential V1 under inflammatory conditions.

Takayoshi Masuoka, Yuka Yamashita, Junko Yoshida, Katsuya Nakano, Masashi Tawa, Matomo Nishio, Takaharu Ishibashi

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Immune drivers of physiological and pathological pain.The Journal of experimental medicine · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. [Neuroimmunomodulation in allergic rhinitis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Takayoshi MasuokaDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.ORCID 0000-0002-1689-8762
Yuka YamashitaDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
Junko YoshidaDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
Katsuya NakanoDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
Masashi TawaDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
Matomo NishioDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
Takaharu IshibashiDepartment of Pharmacology, School of Medicine, Kanazawa Medical University, Uchinada, Ishikawa, Japan.
Kanazawa Medical University · JP

Funding

Japan Society for the Promotion of Science 16K19023Japan Society for the Promotion of Science 17K16992Japan Society for the Promotion of Science 19K07117Japan Society for the Promotion of Science 19K09961Japan Society for the Promotion of Science 19K18895Japan Society for the Promotion of Science 20K09814Kanazawa Medical University S2016-5Kanazawa Medical University S2019-1Nakatomi FoundationSmoking Research Foundation
6 · The paper itself

Abstract

background and purposeGlutamate and metabotropic glutamate (mGlu) receptors on primary sensory neurons are crucial in modulating pain sensitivity. However, it is unclear how inflammation affects mGlu receptor-mediated nociceptive responses. We therefore investigated the effects of mGlu EXPERIMENTAL APPROACH: Effects of a mGlu KEY

resultsPersistent inflammation induced by complete Freund's adjuvant increased the duration of mGlu CONCLUSIONS AND IMPLICATIONS: NGF augments glutamate- and mGlu

Indexed as

Nerve Growth FactorPainTRPV Cation ChannelsA Kinase Anchor ProteinsAnimalsGanglia, SpinalMaleMiceMice, Inbred C57BLPhosphorylationAkap5 protein, mouseA Kinase Anchor ProteinsNerve Growth FactorTRPV Cation Channels

Identifiers

PMID32579702
PMCPMC7443478
OpenAlexW3037544874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.