ArticleInvestigative ophthalmology & visual science2020
Suppression Rather Than Visual Acuity Loss Limits Stereoacuity in Amblyopia.
Article in Investigative ophthalmology & visual science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Research hotspots and trends of amblyopia treatment from 2015 to 2025: a bibliometric analysis.Frontiers in neuroscience · 2025Pooled it
- Dichoptic Perceptual Training and Sensory Eye Dominance Plasticity in Normal Vision.Investigative ophthalmology & visual science · 2021Trial
- "Look Versus See": Does Varying Fellow Eye Contrast Affect Perception of the Amblyopic Eye?Investigative ophthalmology & visual science · 2026Article
- First-order basis of second-order temporal loss in amblyopia.Journal of translational medicine · 2026Article
- Spatiotemporal Dynamics of Binocular Interaction in Anisometropic Amblyopia Revealed by Classification Image.Investigative ophthalmology & visual science · 2026Article
- Macular, Foveal and RNFL Thickness Patterns in Amblyopia: A Comparative Study.Clinical optometry · 2026Article
- Effectiveness of Active Vision Therapy in Children with Bilateral Refractive Amblyopia.Journal of ophthalmic & vision research · 2026Article
- Neurophysiological basis for visual distortions in amblyopia.Frontiers in neuroscience · 2026Review
- Rethinking perceptual distortions in amblyopia: toward a multi-feature, visual-field-wide perspective.Frontiers in neuroscience · 2026Article
- Dynamic Stereopsis Is Abnormal in Treated Anisometropic Amblyopia.Investigative ophthalmology & visual science · 2025Article
- Ebbinghaus Illusion Distortions in Amblyopia: Impairments of Visual Size Processing and Interocular Integration.Investigative ophthalmology & visual science · 2025Article
- Magnocellular-biased interocular integration during onset rivalry in normal vision and binocular imbalance.Journal of vision · 2025Article
- Multi-Feature Mapping of Distortions in Amblyopia With Localized Sampling.Investigative ophthalmology & visual science · 2025Article
- Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study.JMIR serious games · 2025Article
- Amblyopic binocular imbalance quantified by the dichoptic contrast ordering test and dichoptic letters test.Scientific reports · 2025Article
- Femtosecond laser small incision lenticule extraction on binocularity for myopia with glasses-free 3D technique.International journal of ophthalmology · 2025Article
- The hidden impact of myopia severity on interocular suppression in myopia: a cross-sectional study.Frontiers in medicine · 2025Article
- Novel Glasses-Free Distance Stereotest Using Eye Tracking: Evaluation of Sensitivity, Validity, Reliability, and Monocular Cue Masking.Journal of multidisciplinary healthcare · 2025Article
- Evaluating Eye Tracking During Dichoptic Video Viewing With Varied Fellow Eye Contrasts in Amblyopia.Investigative ophthalmology & visual science · 2024Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the influence of interocular suppression and visual acuity loss on stereoacuity in observers with and without abnormal vision development from strabismus or amblyopia. To determine whether stereoacuity improves in amblyopic observers when suppression is neutralized. Methods: Experiment 1: Visual acuity (VA), depth of suppression (contrast ratio [CR]), and stereoacuity (digital random-dot) were tested in adult amblyopic observers (n = 21; age 27 ± 11 years). Experiment 2: VA, stereoacuity, and CR were measured at baseline and through a series of monocular contrast attenuation and Bangerter filter conditions that degrade visual input in participants with normal binocular vision (n = 19; age 31 ± 13 years). Multiple regression models were used to determine relative contribution of VA and CR to stereoacuity in both groups. Experiment 3: stereoacuity was retested in a subsample of amblyopic observers (n = 7) after contrast reduction of the stimulus presented to dominant eye to neutralize suppression. Results: In amblyopic observers, stereoacuity significantly correlated with CR (P < 0.001), but not with interocular VA difference (P = 0.863). In participants with normal vision development, stereoacuity, VA, and CR declined with introduction of monocular Bangerter filter (P < 0.001), and stereoacuity reduced with monocular attenuation of stimulus contrast (P < 0.001). Reduction in stereoacuity correlated with both VA decrement and degraded CR. Stereoacuity significantly improved in amblyopic observers when the contrast to the dominant eye was adjusted based on the contrast ratio. Conclusions: Suppression rather than visual acuity loss limits stereoacuity in observers with abnormal vision development. Stereopsis can be improved when interocular sensory dominance is neutralized.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.