Evidence map›Paper›PMID 32579471›Full record

ArticleAutophagy2021

An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1.

Bora Lee, Hyejin Shin, Ji-Eun Oh, Jaekyoung Park, Mira Park, Seung Chel Yang, Jin-Hyun Jun, Seok-Ho Hong, Haengseok Song, Hyunjung Jade Lim

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  7. When autophagy meets placenta development and pregnancy complications.Frontiers in cell and developmental biology · 2024
    Review
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  15. Review
  16. Autophagy in the uterine vessel microenvironment: Balancing vasoactive factors.Clinical and experimental reproductive medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Bora LeeDepartment of Biomedical Science & Technology, Konkuk University, Seoul, Korea.
Hyejin ShinDepartment of Biomedical Science & Technology, Konkuk University, Seoul, Korea.
Ji-Eun OhDepartment of Veterinary Medicine, Konkuk University, Seoul, Korea.
Jaekyoung ParkDepartment of Biomedical Science & Technology, Konkuk University, Seoul, Korea.
Mira ParkDepartment of Biomedical Science, CHA University, Seongnam, Gyeonggi-do, Korea.ORCID 0000-0003-0690-3828
Seung Chel YangDepartment of Biomedical Science, CHA University, Seongnam, Gyeonggi-do, Korea.
Jin-Hyun JunDepartment of Biomedical Laboratory Science, Eulji University, Seongnam, Gyeonggi-do, Korea.ORCID 0000-0001-9898-4471
Seok-Ho HongDepartment of Internal Medicine, School of Medicine, Kangwon National University, Kangwon-do, Chuncheon, Korea.
Haengseok SongDepartment of Biomedical Science, CHA University, Seongnam, Gyeonggi-do, Korea.ORCID 0000-0002-5027-7310
Hyunjung Jade LimDepartment of Biomedical Science & Technology, Konkuk University, Seoul, Korea.ORCID 0000-0003-2191-666X
Konkuk University · KRCHA University · KREulji University · KRKangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The uterus undergoes vascular changes during the reproductive cycle and pregnancy. Steroid hormone deprivation induces macroautophagy/autophagy in major uterine cell types. Herein, we explored the functions of uterine autophagy using the

Indexed as

AutophagyCapillary PermeabilityAnimalsbeta CateninCellular MicroenvironmentFemaleMiceMice, Inbred C57BLMice, KnockoutNitric Oxide Synthase Type IUterine ArteryUterusVascular Endothelial Growth Factor Abeta CateninCTNNB1 protein, mouseNitric Oxide Synthase Type INos1 protein, mouseVascular Endothelial Growth Factor Avascular endothelial growth factor A, mouseAtg7autophagypermeabilityuterusvascular factor

Identifiers

PMID32579471
PMCPMC8354601
OpenAlexW3036926175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.