ArticleJournal of biological rhythms2020
Genetic Associations of Chronotype in the Finnish General Population.
Article in Journal of biological rhythms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Rotating Night Shift Work and Risk of Incident Cardiovascular Disease and Mortality by Chronotype: A Prospective Cohort Study in Nurses' Health Study II.medRxiv : the preprint server for health sciences · 2026Article
- Chronotype, Genetic Risk, Lifestyle, and Risk of Depression and Anxiety: A Prospective Cohort Study.MedComm · 2026Article
- Chronotype, Life's Essential 8, and Risk of Cardiovascular Disease: A Prospective Cohort Study in UK Biobank.Journal of the American Heart Association · 2026Article
- Chronotype and Cardiovascular Disease Risk Factors among Middle-aged and Older Adults: An observational and Mendelian Randomization Study.medRxiv : the preprint server for health sciences · 2026Article
- Preventive circadian medicine: improving health with sleep checkups.Npj biological timing and sleep · 2025Review
- Sex- and Substance-Specific Associations of Circadian-Related Genes with Addiction in the UK Biobank Cohort Implicate Neuroplasticity Pathways.Brain sciences · 2024Article
- The genetic architecture of the human hypothalamus and its involvement in neuropsychiatric behaviours and disorders.Nature human behaviour · 2024Article
- Association between CLOCK gene polymorphisms with circadian rhythm, chrononutrition, dietary intake, and metabolic parameters in adolescents.Frontiers in public health · 2024Article
- Role of polygenic risk scores in the association between chronotype and health risk behaviors.BMC psychiatry · 2023Article
- Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged U.S. Women : A Prospective Cohort Study.Annals of internal medicine · 2023Article
- Influence of Environmental Exposure to Steel Waste on Endocrine Dysregulation andInternational journal of environmental research and public health · 2023Article
- Intrinsic individual variation in daily activity onset and plastic responses on temporal but not spatial scales in female great tits.Scientific reports · 2022Article
- Causality of genetically determined metabolites on anxiety disorders: a two-sample Mendelian randomization study.Journal of translational medicine · 2022Article
- Morningness-eveningness preference and shift in chronotype during COVID-19 as predictors of mood and well-being in university students.Personality and individual differences · 2022Article
- Chronotype, circadian rhythm, and psychiatric disorders: Recent evidence and potential mechanisms.Frontiers in neuroscience · 2022Review
- The relationship between chronotypes and musculoskeletal problems in male automobile manufacturing workers.Annals of occupational and environmental medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals with a later chronotype (evening types) tend to have unhealthier behaviors and increased morbidity and mortality as compared with those with an earlier chronotype (morning types). However, the role of genetics in explaining evening types' adverse health and health behavior is unclear. Our aim was to study genetic associations of chronotype among 8433 Finns from the cross-sectional National FINRISK 2007 and 2012 studies. First, we studied associations between chronotype and 20 key clock genes with a candidate-gene approach and then performed a full genome-wide association study (GWAS) of chronotype. We also developed a genetic risk score (GRS) for chronotype based on 313 single nucleotide polymorphisms (SNPs) that have previously been associated with chronotype. Chronotype was assessed with a shortened version of Horne and Östberg's Morningness-Eveningness Questionnaire (sMEQ), and for comparison, we also used the single self-evaluation question on chronotype from the questionnaire. Linear and logistic regression was used for statistical analysis assuming additive effects. The clock gene analysis revealed 1 independent association signal within
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.