ArticleGenome biology and evolution2020
A New High-Quality Draft Genome Assembly of the Chinese Cordyceps Ophiocordyceps sinensis.
Article in Genome biology and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed.
- Structural Diversity and Differential Natural Pairings of MAT1-1-1 and MAT1-2-1 Proteins Essential for Sexual Reproduction inInternational journal of molecular sciences · 2026Article
- Transcriptomic Profiling of Developmental Stages and Screening of Candidate Genes inJournal of fungi (Basel, Switzerland) · 2026Article
- Telomere-to-telomere genome assembly of Metarhizium acridum provides insights into Metarhizium genome evolution.BMC genomics · 2026Article
- Integrative Multi-Omics Reveals Microbiome and Genome Streamlining Underlie Ecological Divergence in Chinese and XinjiangInternational journal of molecular sciences · 2026Article
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- Research Progress on the Regulation and Developmental Utilization of Bioactive Metabolites Synthesis inJournal of fungi (Basel, Switzerland) · 2025Review
- Whole genome sequencing and resequencing provide insight into the genetic structure of wild Ophiocordyceps sinensis.BMC genomics · 2025Article
- Haplotype-Phased Chromosome-Level Genome Assembly ofJournal of fungi (Basel, Switzerland) · 2025Article
- A Review of Genomic, Transcriptomic, and Proteomic Applications in Edible Fungi Biology: Current Status and Future Directions.Journal of fungi (Basel, Switzerland) · 2025Review
- Three-Dimensional Structural Heteromorphs of Mating-Type Proteins inJournal of fungi (Basel, Switzerland) · 2025Article
- Three new species ofMycoKeys · 2025Article
- Translation of Mutant Repetitive Genomic Sequences inInternational journal of molecular sciences · 2024Article
- Establishment of anCurrent issues in molecular biology · 2024Article
- Mutations and Differential Transcription of Mating-Type and Pheromone Receptor Genes inBiology · 2024Article
- Selection and validation of reference genes for RT-qPCR in ophiocordyceps sinensis under different experimental conditions.PloS one · 2024Article
- Characterization of the Biosynthetic Gene Cluster for the Ribosomally Synthesized Cyclic Peptide Epichloëcyclins inJournal of agricultural and food chemistry · 2023Article
- Transcriptome and metabonomics combined analysis revealed the energy supply mechanism involved in fruiting body initiation in Chinese cordyceps.Scientific reports · 2023Article
- Article
- Article
- Isolation of strains and their genome sequencing to analyze the mating system of Ophiocordyceps robertsii.PloS one · 2023Article
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10 authors.
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Abstract
Ophiocordyceps sinensis (Berk.) is an entomopathogenic fungus endemic to the Qinghai-Tibet Plateau. It parasitizes and mummifies the underground ghost moth larvae, then produces a fruiting body. The fungus-insect complex, called Chinese cordyceps or "DongChongXiaCao," is not only a valuable traditional Chinese medicine, but also a major source of income for numerous Himalayan residents. Here, taking advantage of rapid advances in single-molecule sequencing, we assembled a highly contiguous genome assembly of O. sinensis. The assembly of 23 contigs was ∼110.8 Mb with a N50 length of 18.2 Mb. We used RNA-seq and homologous protein sequences to identify 8,916 protein-coding genes in the IOZ07 assembly. Moreover, 63 secondary metabolite gene clusters were identified in the improved assembly. The improved assembly and genome features described in this study will further inform the evolutionary study and resource utilization of Chinese cordyceps.
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