ArticleeLife2020
Mouse brain transcriptome responses to inhaled nanoparticulate matter differed by sex and
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Urban PMMolecular neurobiology · 2026Article
- Transcriptomics insight into occupational exposure to engineered nanoparticles.Nanomedicine (London, England) · 2025Article
- Age- and ApoE Genotype-Dependent Transcriptomic Responses to OInternational journal of molecular sciences · 2025Article
- Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population-based data.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Inhaled Pollutants of the Gero-Exposome and Later-Life Health.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Review
- Systems Genetics Analyses Reveals Key Genes Related to Behavioral Traits in the Striatum of CFW Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Peripheral HMGB1 is linked to OAlzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- ApoE Isoforms Inhibit Amyloid Aggregation of Proinflammatory Protein S100A9.International journal of molecular sciences · 2024Article
- Exploring Single-Cell Exposomics by Mass Spectrometry.Environmental science & technology · 2023Review
- Exposure to quasi-ultrafine particulate matter accelerates memory impairment and Alzheimer's disease-like neuropathology in the AppNL-G-F knock-in mouse model.Toxicological sciences : an official journal of the Society of Toxicology · 2023Article
- Maternal exposure to air pollution alters energy balance transiently according to gender and changes gut microbiota.Frontiers in endocrinology · 2023Article
- Cardiac NF-κB Acetylation Increases While Nrf2-Related Gene Expression and Mitochondrial Activity Are Impaired during the Progression of Diabetes in UCD-T2DM Rats.Antioxidants (Basel, Switzerland) · 2022Article
- Artemisia argyi extract alleviates inflammation in a DSS-induced colitis mouse model and enhances immunomodulatory effects in lymphoid tissues.BMC complementary medicine and therapies · 2022Article
- Gene-Environment Interactions and Stochastic Variations in the Gero-Exposome.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021Article
- Cerebral cortex and blood transcriptome changes in mouse neonates prenatally exposed to air pollution particulate matter.Journal of neurodevelopmental disorders · 2021Article
- Air Pollution Particulate Matter Exposure and Chronic Cerebral Hypoperfusion and Measures of White Matter Injury in a Murine Model.Environmental health perspectives · 2021Article
- The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer's Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats.Environmental health perspectives · 2021Article
- The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humans.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Article
- Air Pollution Particulate Matter Amplifies White Matter Vascular Pathology and Demyelination Caused by Hypoperfusion.Frontiers in immunology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Amin HaghaniLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.ORCID 0000-0002-6052-8793
Mafalda CacciottoloLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Kevin R DotyZilkha Neurogenetic Institute, Department of Physiology and Neuroscience, Keck School of Medicine of the University of Southern California, Los Angeles, United States.
Carla D'AgostinoLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Max ThorwaldLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Nikoo SafiLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Morgan E LevineDepartment of Pathology, Yale School of Medicine, New Haven, United States.ORCID 0000-0001-9890-9324
Constantinos SioutasDepartment of Civil and Environmental Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, United States.
Terrence C TownZilkha Neurogenetic Institute, Department of Physiology and Neuroscience, Keck School of Medicine of the University of Southern California, Los Angeles, United States.
Henry Jay FormanLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Hongqiao ZhangLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Todd E MorganLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.
Caleb E FinchLeonard Davis School of Gerontology, University of Southern California, Los Angeles, United States.ORCID 0000-0002-7617-3958
University of Southern California · USYale University · US
Funding
VASCULAR RISK AND COGNITIVE STATUS IN A LATINO POPULATIONP50AG005142 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRASKIE, MEREDITH NICOLE · 1985 to 2019
$41.0MUSCADRC Diversity Supplement PachicanoP30AG066530 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HELENA Chang CHUI, ARTHUR W TOGA · 2020 to 2026
$27.8MRESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2MUrban Air Pollution and Pathological Brain Aging: A Nationwide Twin Study in MenP01AG055367 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, JIU-CHIUAN, FINCH, CALEB E · 2018 to 2022
$11.5MUSC Geroscience Training in the Biology of AgingT32AG052374 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sean P CURRAN · 2016 to 2026
$5.3MPeripheral TGF-beta Pathway Inhibitor Therapy in Alzheimer's RatsR01NS076794 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHANG, KAREN T, CHEN, JEANNIE · 2011 to 2021
$4.9MMolecular Networks Underlying Resilience to Alzheimer's Disease Among APOE E4 CarriersR01AG057912 · NIA · YALE UNIVERSITY · PI GAITERI, CHRISTOPHER A., HIGGINS-CHEN, ALBERT TZONGYANG · 2017 to 2021
$4.5MIdentifying the molecular systems, networks, and key molecules that underlie cognitive resilienceR01AG057911 · NIA · UPSTATE MEDICAL UNIVERSITY · PI GAITERI, CHRISTOPHER A. · 2017 to 2021
$3.8MAmyloid and inflammation: modulation by apoE, gender, air pollution, and drugsRF1AG051521 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2015 to 2015
$3.0MInnate Immune IL-10/STAT3 Signaling in Alzheimer's DiseaseRF1AG053982 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHANG, KAREN T, CHEN, JEANNIE · 2017 to 2017
$2.8MMolecular mechanisms and social constructs: How genes and environment regulate the rate of agingR00AG052604 · NIA · YALE UNIVERSITY · PI LEVINE, MORGAN ELYSE, TIGNANELLI, CHRISTOPHER J · 2017 to 2020
$866kNIA NIH HHS 1R01AG057912-01NIA NIH HHS 1RF1AG053982-01A1NIA NIH HHS 4R00AG052604-02NIA NIH HHS P01 AG055367NIA NIH HHS P30 AG066530NIA NIH HHS P50 AG005142NIA NIH HHS P50AG05142NIA NIH HHS R00 AG052604NIA NIH HHS R01AG051521NIA NIH HHS R01 AG057911NIA NIH HHS R01 AG057912NIA NIH HHS RF1 AG051521NIA NIH HHS RF1 AG053982NIA NIH HHS T32 AG000037NIA NIH HHS T32 AG052374NINDS NIH HHS R01 NS076794
Abstract
The neurotoxicity of air pollution is undefined for sex and
Indexed as
Administration, InhalationAir PollutantsAnimalsApolipoproteins EBrainFemaleGene Expression RegulationMaleMiceMice, Inbred C57BLMice, TransgenicNanoparticlesNF-E2-Related Factor 2NF-kappa BTranscriptomeAir PollutantsApoe protein, mouseApolipoproteins ENfe2l2 protein, mouseNF-E2-Related Factor 2NF-kappa Bair pollutionAPOEcomputational biologymouseneurosciencenf-kbNrf2sexsystems biologytranscriptome
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.