ArticleeLife2020
Slow oscillation-spindle coupling predicts enhanced memory formation from childhood to adolescence.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
72 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Memory retention following acoustic stimulation in slow-wave sleep: a meta-analytic review of replicability and measurement quality.Frontiers in sleep · 2023Pooled it
- Efficacy and mechanisms of repeated closed-loop auditory exposure during slow-wave sleep for internet gaming disorder.Molecular psychiatry · 2025Trial
- Sleep forms flexible context representations in toddlers.Nature communications · 2026Article
- Sleep spindle deficits in childhood absence epilepsy improve with antiseizure treatment and disease resolution.bioRxiv : the preprint server for biology · 2026Article
- Human brain-wide activation of sleep rhythms.eLife · 2026Article
- Theta oscillations tag episodic memories for sleep-dependent consolidation.PLoS biology · 2026Article
- Dream content and slow waves benefit prey against predator in a video game confrontation.Scientific reports · 2026Article
- Auditory-evoked changes in slow oscillations and spindles correlate with memory consolidation in children with epilepsy and controls.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Article
- Modulating sleep: slow oscillation and spindle stimulation effects on physiology and memory.NPJ science of learning · 2026Article
- Temporal sleep spindle clustering and slow-oscillation coupling in motor memory consolidation and generalization.Communications biology · 2026Article
- Hippocampal interictal discharges induce frontal spindles and enhance spindle-slow oscillation coupling in temporal lobe epilepsy.Clinical neurophysiology practice · 2026Article
- Decoding visual object recognition from EEG signals.PloS one · 2026Article
- Using a wearable EEG device to examine age trends in sleep macro- and micro-architecture across adolescence.bioRxiv : the preprint server for biology · 2025Article
- rTMS Improves Cognition in Patients With Self-Limited Epilepsy With Centrotemporal Spikes With Electrical Status Epilepticus in Sleep via Increase of the Sleep Spindle.CNS neuroscience & therapeutics · 2025Article
- Phase-Amplitude Coupling in Sleep EEG-Stable Trait or Shaped by Experience? (Commentary on Cross et al., 2025).The European journal of neuroscience · 2025Article
- Article
- Competitive roles of slow/delta oscillation-nesting-mediated sleep disruption under acute methamphetamine exposure in monkeys.Journal of Zhejiang University. Science. B · 2025Article
- Pediatric sleep electrophysiology: Using polysomnography in developmental cognitive neuroscience.Developmental cognitive neuroscience · 2025Review
- Phase-Amplitude Coupling of NREM Sleep Oscillations Shows Between-Night Stability and is Related to Overnight Memory Gains.The European journal of neuroscience · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Precise temporal coordination of slow oscillations (SO) and sleep spindles is a fundamental mechanism of sleep-dependent memory consolidation. SO and spindle morphology changes considerably throughout development. Critically, it remains unknown how the precise temporal coordination of these two sleep oscillations develops during brain maturation and whether their synchronization indexes the development of memory networks. Here, we use a longitudinal study design spanning from childhood to adolescence, where participants underwent polysomnography and performed a declarative word-pair learning task. Performance on the memory task was better during adolescence. After disentangling oscillatory components from 1/f activity, we found frequency shifts within SO and spindle frequency bands. Consequently, we devised an individualized cross-frequency coupling approach, which demonstrates that SO-spindle coupling strength increases during maturation. Critically, this increase indicated enhanced memory formation from childhood to adolescence. Our results provide evidence that improved coordination between SOs and spindles indexes the development of sleep-dependent memory networks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.