Evidence map›Paper›PMID 32579086›Full record

Trial reportPalliative medicine2020

Mouthpiece ventilation in the management of dyspnea: A single-arm pilot study.

Juho T Lehto, Sirpa Leivo-Korpela, Tarja Korhonen, Heidi A Rantala, Hanna Raunio, Tiina Lyly-Yrjänäinen, Lauri Lehtimäki

Registry-linked trialOpen access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Palliative medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03012737 (Palliation of Dyspnea With Mouth Piece Ventilation), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03012737 naterminatednot on this map

Palliation of Dyspnea With Mouth Piece Ventilation

TypeinterventionalSponsorTampere University HospitalRan2017 to 2019Enrolled22ConditionsDyspneaArmsTrilogy 100 ® (Philips Respironics)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Juho T LehtoFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0001-8519-7372
Sirpa Leivo-KorpelaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tarja KorhonenPirkanmaa Hospice, Palliative Care Centre, Tampere University Hospital, Tampere, Finland.
Heidi A RantalaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Hanna RaunioPalliative Care Centre and Tays Cancer Centre, Department of Oncology, Tampere University Hospital, Tampere, Finland.
Tiina Lyly-YrjänäinenPalliative Care Centre and Tays Cancer Centre, Department of Oncology, Tampere University Hospital, Tampere, Finland.
Lauri LehtimäkiFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tampere University · FITampere University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNoninvasive ventilation may relieve dyspnea in advanced diseases, but noninvasive ventilation through mouthpiece has not been tested in palliative care.

aimTo assess the feasibility of mouthpiece ventilation in relieving dyspnea among patients with advanced disease.

designIn this prospective single-arm pilot study, the change in dyspnea by mouthpiece ventilation was measured with numeric rating scale (0-10) and 100-mm visual analogue scale. Overall, benefit and adverse events of the therapy were also assessed. SETTING/

participantsTwenty-two patients with an advanced disease and dyspnea from the Tampere University Hospital or Pirkanmaa Hospice were treated with mouthpiece ventilation. The patients used mouthpiece ventilation as long as they preferred, but for a minimum of 5 min.

resultsAfter the treatment period lasting a median of 13.5 min, mean decrease in dyspnea was -1.1 (95 % confidence interval = -2.2 to -0.1,

conclusionMouthpiece ventilation is feasible and may relieve dyspnea in some patients with an advanced disease. Further studies are needed, and these might concentrate on stable patients in early palliative care. Before initiation, this study was registered at clinicaltrials.gov (study no. NCT03012737).

Indexed as

DyspneaNoninvasive VentilationPalliative CareFemaleHumansPilot ProjectsProspective StudiesDyspneamouthpiece ventilationnoninvasive ventilationpalliative carepalliative medicine

Identifiers

PMID32579086
PMCPMC7495670
OpenAlexW3037150015

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.