ArticleJournal of the American Heart Association2020
Healthy Lifestyle for Prevention of Premature Death Among Users and Nonusers of Common Preventive Medications: A Prospective Study in 2 US Cohorts.
Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Lifestyle behaviors and risk of cardiovascular disease and prognosis among individuals with cardiovascular disease: a systematic review and meta-analysis of 71 prospective cohort studies.The international journal of behavioral nutrition and physical activity · 2024Pooled it
- Educational inequalities in trajectories of co-occurring behavioral health risk factors over four years: a latent class growth analysis.BMC public health · 2025Trial
- A simulation study of the impact of population-wide lifestyle modifications on life expectancy in the Chinese population.Nature communications · 2025Article
- The efferocytosis process in aging: Supporting evidence, mechanisms, and therapeutic prospects for age-related diseases.Journal of advanced research · 2025Review
- Fruit but not vegetable consumption is beneficial for low prevalence of colorectal polyps in a high-risk population: findings from a Chinese Lanxi Pre-colorectal Cancer Cohort study.European journal of nutrition · 2024Article
- Hospital admission and mortality rates for ischemic heart disease in Thailand: 2012-2021.BMC research notes · 2024Article
- Healthy lifestyle, statin, and mortality in people with high CVD risk: A nationwide population-based cohort study.American journal of preventive cardiology · 2024Article
- Impact of Active vs Passive Statin Selection for Primary Prevention: The CorCal Vanguard Trial.JACC. Advances · 2023Article
- Behavior-related health risk factors, mental disorders and mortality after 20 years in a working aged general population sample.Scientific reports · 2023Article
- Preventive Medication Use among Adults Aged 40 and over in the United States: National Health and Nutrition Examination Survey, 2015-2018.Healthcare (Basel, Switzerland) · 2022Article
- Combined lifestyle, mental health, and mortality in US cancer survivors: a national cohort study.Journal of translational medicine · 2022Article
- Association of preserved vegetable consumption and prevalence of colorectal polyps: results from the Lanxi Pre-colorectal Cancer Cohort (LP3C).European journal of nutrition · 2022Article
- Association of healthy lifestyle and all-cause mortality according to medication burden.Journal of the American Geriatrics Society · 2022Article
- Protocol of the Inner Mongolian Healthy Aging Study (IMAGINS): a longitudinal cohort study.BMC public health · 2022Article
- Association of Meat Subtypes With Colorectal Polyp Prevalence: Finding From the Lanxi Pre-colorectal Cancer Cohort in China.Frontiers in nutrition · 2022Article
- Enhancing preventive medicine over curative medicine: Role of telemedicine.Public health in practice (Oxford, England) · 2021Article
- Article
- Healthy Lifestyle for Prevention of Premature Death Among Users and Nonusers of Common Preventive Medications: A Prospective Study in 2 US Cohorts.Journal of the American Heart Association · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Background It remains unknown whether individuals who regularly use preventive medications receive the same benefit from healthy lifestyle as those who do not use medications. We aimed to examine the associations of healthy lifestyle with mortality according to use of major preventive medications, including aspirin, antihypertensives, and lipid-lowering medications. Methods and Results Among 79 043 women in the Nurses' Health Study (1988-2014) and 39 544 men in the Health Professionals Follow-up Study (1986-2014), we defined a healthy lifestyle score based on body mass index, smoking, physical activity, diet, and alcohol intake. We estimated multivariable hazard ratios (HRs) and population-attributable risks of death from any cause, cardiovascular disease, cancer, and other causes in relation to healthy lifestyle according to medication use. We documented 35 195 deaths. A similar association of healthy lifestyle score with lower all-cause mortality was observed among medication users (HR, 0.82 per unit increment; 95% CI, 0.81-0.82) and nonusers (HR, 0.81; 95% CI, 0.79-0.83) (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.