ReviewHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2020
Pharmacological Approach to Smoking Cessation: An Updated Review for Daily Clinical Practice.
Review in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05484505 (Effectiveness of Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan- A Randomized Controlled Trial), which is not on this map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Preloaded Combination Nicotine Replacement Therapy on Smoking Cessation of Adult Population in Kazakhstan- A Randomized Controlled Trial
Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Pooled it
- Latin-American guidelines of recommendations at discharge from an acute coronary syndrome.Archivos de cardiologia de Mexico · 2024Guideline
- Efficacy of Motivational Interviewing and Brief Interventions on tobacco use among healthy adults: A systematic review of randomized controlled trials.Investigacion y educacion en enfermeria · 2022Pooled it
- When primary care providers and smokers meet: a systematic review and metasynthesis.NPJ primary care respiratory medicine · 2021Pooled it
- Efficacy and safety of physical therapy in patients with stage III COPD during ambulatory rehabilitation.Journal of medicine and life · 2023Trial
- Implementation of Specialty Tobacco Use Disorder Services in a Community Health Setting: Support for Enhanced Prescription Practices.Journal of addiction medicineTrial
- Cerebrovascular Accident Risk in Survivors of Head and Neck Cancer: JACC CardioOncology State-of-the-Art Review.JACC. CardioOncology · 2026Review
- Factors associated with intention to quit smoking in Indonesia: findings from a cross-sectional Global Adult Tobacco Survey.Korean journal of family medicine · 2026Article
- One-year comparative effectiveness of bupropion and nicotine replacement therapy in smoking cessation: A prospective observational cohort study in Turkey.Pakistan journal of medical sciences · 2026Article
- GLP-1 receptor agonists for smoking cessation: a narrative review of weight management potential.Annals of medicine and surgery (2012) · 2026Article
- Review
- A Pharmacological Update and Safety Analysis of Medications for Smoking Cessation: Which Ones to Use?Current pharmaceutical design · 2026Review
- Cannabinoid-based Pharmacology for the Management of Substance Use Disorders.Current topics in behavioral neurosciences · 2026Review
- The impact of nicotine dependence and smoking pattern changes on short- and long-term smoking cessation outcomes: The role of sociodemographic factors in a retrospective cohort study.Tobacco induced diseases · 2026Article
- Article
- Therapeutic Potential of Methanolic Extract ofJournal of pharmacopuncture · 2025Article
- Dopaminergic Genetic Variation and Trait Impulsivity: The Role ofLife (Basel, Switzerland) · 2025Article
- Article
- Explainable artificial intelligence driven insights into smoking prediction using machine learning and clinical parameters.Scientific reports · 2025Article
- Rhoifolin as a potential anxiolytic drug for the effects of nicotine withdrawal: beneficial effects on behavior, neuroinflammation, and oxidative stress.Metabolic brain disease · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tobacco use is one of the major public health concerns and it is the most preventable cause of morbidity and mortality worldwide. Smoking cessation reduces subsequent cardiovascular events and mortality. Smoking is a real chronic disorder characterized by the development of an addiction status mainly due to nicotine. This condition makes the smokers generally unable to quit smoking without help. Different strategies are available to treat smoking dependence that include both non-pharmacological (behavioral counselling) and pharmacological therapies. Currently, it is well accepted that smoking cessation drugs are effective and safe in real-world settings. Nicotine replacement therapy (NRT), varenicline, bupropion and cytisine are the main pharmacological strategies available for smoking cessation. Their efficacy and safety have been proved even in patients with chronic cardiovascular disease. Each of these drugs has peculiar characteristics and the clinician should customize the smoking cessation strategy based on currently available scientific evidence and patient's preference, paying particular attention to those patients having specific cardiovascular and psychiatric comorbidities. The present document aims to summarize the current viable pharmacological strategies for smoking cessation, also discussing the controversial issue regarding the use of alternative tobacco products, in order to provide useful practical indications to all physicians, mainly to those involved in cardiovascular prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.