Evidence map›Paper›PMID 32578161›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2020

Peripheral Blood Leukocyte Telomere Length and Endometriosis.

Naoko Sasamoto, Jennifer Yland, Allison F Vitonis, Daniel W Cramer, Linda J Titus, Immaculata De Vivo, Stacey A Missmer, Kathryn L Terry

Open access · greenAbstract read
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Naoko SasamotoDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA. nsasamoto@bwh.harvard.edu.ORCID 0000-0002-4526-2181
Jennifer YlandDepartment of Epidemiology, Boston University, Boston, MA, USA.
Allison F VitonisDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA.
Daniel W CramerDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA.
Linda J TitusDepartment of Epidemiology and Pediatrics, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Immaculata De VivoDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Stacey A MissmerDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Kathryn L TerryDepartment of Obstetrics and Gynecology, Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, MA, 02115, USA.
Brigham and Women's Hospital · USBoston University · USDartmouth College · USHarvard University · US

Funding

What is Endometriosis? Deep Phenotyping to Advance Diagnosis and TreatmentR01HD094842 · NICHD · MICHIGAN STATE UNIVERSITY · PI FAZLEABAS, ASGERALLY T., MISSMER, STACEY ANN · 2018 to 2022
$4.2M
Boston Center for Endometriosis (US) Trainee AwardNICHD NIH HHS R01 HD094842Ovarian Cancer Research Fund (US) Liz Tilberis Award
6 · The paper itself

Abstract

Endometriosis is a common gynecologic disease defined by the presence of endometrial-like tissue outside the uterine cavity. While its etiology is largely unknown, accumulating evidence suggests that inflammation plays a major role. Our objective was to investigate the association between peripheral blood leukocyte telomere length (LTL) and endometriosis using data from two large population-based studies, the New England Case-Control Study (NEC; n = 877) and the National Health and Nutrition Examination Survey (NHANES; n = 2268). NEC control participants were identified through a combination of random digit dialing, drivers' license lists, and town resident lists. In NHANES, selection algorithms were used to identify a nationally representative sample. Blood samples and demographic, reproductive, and health-related information were available from both data sources. Endometriosis was defined as self-reported of physician-diagnosed endometriosis. LTL was measured using quantitative polymerase chain reaction. Multivariable logistic regression was used to calculate odds ratios (OR) and 95% confidence intervals (CI) for the association between LTL and endometriosis. Shorter LTL was associated with greater odds of history of endometriosis. In NEC, women with the shortest LTL tertile compared with the longest had a 2.5-fold greater odds of endometriosis (OR

Indexed as

TelomereAdultAlgorithmsCase-Control StudiesEndometriosisFemaleHumansLeukocytes, MononuclearMiddle AgedNutrition SurveysEndometriosisInfertilityLeukocyte telomere lengthMenstrual pain

Identifiers

PMID32578161
PMCPMC7483746
OpenAlexW3037630680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.