Evidence map›Paper›PMID 32578069›Full record

ArticleNeuroscience bulletin2020

Iron Aggravates the Depressive Phenotype of Stressed Mice by Compromising the Glymphatic System.

Shanshan Liang, Yan Lu, Zexiong Li, Shuai Li, Beina Chen, Manman Zhang, Binjie Chen, Ming Ji, Wenliang Gong, Maosheng Xia and 3 more

Abstract readLetter
In one paragraph

Article in Neuroscience bulletin, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Astrocytic KFrontiers in aging neuroscience · 2026
    Review
  5. Article
  6. Review
  7. Aqueous and Ethanol Extracts ofAdvances in pharmacological and pharmaceutical sciences · 2025
    Article
  8. The periaxonal space as a conduit for cerebrospinal fluid flow to peripheral organs.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Review
  11. Review
  12. Brain Iron Homeostasis and Mental Disorders.Antioxidants (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Article
  15. A novel murine model of mania.Molecular psychiatry · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Shanshan LiangPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Yan LuKey Laboratory of the Ministry of Health in Congenital Malformation, The Affiliated Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Zexiong LiPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Shuai LiPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Beina ChenPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Manman ZhangPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Binjie ChenPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Ming JiPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Wenliang GongPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China.
Maosheng XiaDepartment of Orthopedics, The First Hospital, China Medical University, Shenyang, 110001, China.
Alexei VerkhratskyPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China. Alexej.Verkhratsky@manchester.ac.uk.
Xu WuDepartment of Forensic Pathology, School of Forensic Medicine, China Medical University, Shenyang, 110122, China. xwu@cmu.edu.cn.
Baoman LiPractical Teaching Center, School of Forensic Medicine, China Medical University, Shenyang, 110122, China. bmli@cmu.edu.cn.ORCID 0000-0002-3959-9570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDepressionGlymphatic SystemIronMicePhenotypeStress, PsychologicalIron

Identifiers

PMID32578069
PMCPMC7719143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.