Evidence map›Paper›PMID 32578044›Full record

ArticleDigestive diseases and sciences2021

Elimination of Dietary Triggers Is Successful in Treating Symptoms of Gastroesophageal Reflux Disease.

Cesare Tosetti, Edoardo Savarino, Edoardo Benedetto, Rudi De Bastiani, Study Group for the Evaluation of GERD Triggering Foods

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Assessment and treatment of reflux-like symptoms in the community: a multidisciplinary perspective.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
  8. Article
  9. Review
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  14. Reviewing the User-Centered Design Process for a Comprehensive Gastroesophageal Reflux Disease (GERD) App.International journal of environmental research and public health · 2022
    Article
  15. Review
  16. The tapestry of reflux syndromes: translating new insight into clinical practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cesare TosettiNational Health System, Group for Primary Care Gastroenterology (GIGA-CP), Belluno, Italy.
Edoardo SavarinoGastroenterology Unit, Department of Surgery, Oncology and Gastroenterology - DiSCOG, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy. edoardo.savarino@unipd.it.
Edoardo BenedettoNational Health System, Group for Primary Care Gastroenterology (GIGA-CP), Belluno, Italy.
Rudi De BastianiNational Health System, Group for Primary Care Gastroenterology (GIGA-CP), Belluno, Italy.
Study Group for the Evaluation of GERD Triggering Foods

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between aliments and pathophysiological abnormalities leading to gastroesophageal reflux disease (GERD) symptoms elicitation is unclear. Nevertheless, patients often report symptoms after ingestion of specific foods.

aimsTo identify in primary care setting the presence of foods able to trigger GERD symptoms, and evaluate whether a consequent specific food elimination diet may result in clinical improvement.

methodsDiagnosis of GERD and quantification of reflux symptoms were done according to GERD-Q questionnaire (positive when > 8). During clinical data collection, patients were asked to report aliments associated with their symptoms. Also, a precompiled list of additional foods was administered to them. Then, patients were requested to eliminate the specific foods identified, and to come back for follow-up visit after 2 weeks when GERD-Q questionnaire and clinical data collection were repeated.

resultsOne-hundred GERD (mean GERD-Q score 11.6) patients (54 females, mean age 48.7 years) were enrolled. Eighty-five patients reported at least one triggering food, mostly spicy foods (62%), chocolate (55%), pizza (55%), tomato (52%), and fried foods (52%). At follow-up visit, the diagnosis of GERD was confirmed in only 55 patients, and the mean GERD-Q score decreased to 8.9. Heartburn reporting decreased from 93 to 44% of patients, while regurgitation decreased from 72 to 28%. About half of the patients agreed to continue with only dietary recommendations.

conclusionsMost patients with GERD can identify at least one food triggering their symptoms. An approach based on abstention from identified food may be effective in the short term.

Indexed as

AdolescentAdultAgedAged, 80 and overDietFemaleGastroesophageal RefluxHumansMaleMiddle AgedPredictive Value of TestsPrimary Health CareProspective StudiesRisk AssessmentRisk FactorsSurveys and QuestionnairesFoodGastroesophageal reflux diseaseHeartburnPrimary careRegurgitationSymptoms

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.